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Department of Helminthology, FTM
 
  Faculty Staff
 
 
Associate Professor Paron Dekumyoy  
Name: Paron Dekumyoy
Position: Associate Professor
Department: Helminthology
E-mail: tmpdk@mucc.mahidol.ac.th
   
 
Field of Expertise   |   Publications   |   Academic Qualification   |   Award
 
       
2016
  Thaenkham U, Phuphisut O, Nuamtanong S, Yoonuan T, Sa-Nguankiat S, Vonghachack Y, Belizario VY, Dung DT, Dekumyoy P, Waikagul J. Genetic differences among Haplorchis taichui populations in Indochina revealed by mitochondrial COX1 sequences. J Helminthol. 2016 Jul 14:1-8.  
       
    Vitta A, Dekumyoy P, Komalamisra C, Kalambaheti T, Yoshino T. Cloning and expression of a 16kDa recombinant protein from Angiostrongylus cantonensis for use in immunoblot diagnosis of human angiostronglyloasis. Parasitology Research doi: 10.1016/j.parint.2016.08.002  
       
    Vitta A, Srisongcram N, Thiproaj J, Wongma A, Polsut W, Fukruksa C, Yimthin T, Mangkit B, Thansisai A, Dekumyoy P. Phylogeny of Angiostrongylus cantonensis in Thailand based on cytochrome c oxidase subunit l gene sequence. Southeast Asian Journal of Tropical Medicine and Public Health 2016; 47(3): 377-86.  
       
    Yoonuan T, Nuamtanong S, Dekumyoy P. Phuphisut O, Adisakwattana P. Molecular and immunological characterization of cathepsin L-linke cysteine protease of Paragonimus pseudoheterotremus. Parasitology Research doi: 10.1007/s00436-016-523-x  
       
2015
  Hung MN, Huang HW, Dekumyoy P, Pakdee W, Lee YS, Ji DD. First case of neurognathostomiasis in Taiwan-A Thai laborer presenting with eosinophilic meningitis and intracranial hemorrhage . Journal of the Formosan Medical Association 2015; 114(12): 1280-4.  
       
2014
  Chumsang N, Dekumyoy P, Waikagul J, Watthanakulpanich D, Sato M. IgG4: The best immunoglobulin to diagnosis of sparganosis. Graduate Research Conference, Khon Kaen University 2014; 108(2): 71-6.  
       
    Ito A, Wandra T, Li T, Dekumyoy P, Nkouawa A, Okamto M, Budke CM. The present situation of human taeniases and cysticercosis in Asia. Recent Pat Antiinfect Drug Discov. Recent Patents on Anti-Infective Drug Discovery 2014; 9(3): 173-85.  
       
    Maek-a-Nantawat W, Phonrat B, Busssaratid V, Nuamtanong S, Pakdee W, Dekumyoy P. Diagnosisi of gnathostomiasis by skin testing using partially purified specific antigen and total IgE levels. Transactions of the Royal Society of Tropical Medicine and Hygiene 2014; 108(2): 71-6.  
       
    Maipanich W, Dekumyoy P, Sa-nguankiat S, Pubampen S, Poodeepiyasawat A, Kusolsuk T, Thaenkham U, Watthanakulpanich D. Houseflies with helminthic objects, good indicator of an unsanitary environment. JITMM 2013. 2014; Vol.3: 40-41  
       
    Wongkamchai S, Nochote H, Foongladda S, Dekumyoy P, Thammapalo S, Boitano JJ, Choochote W. A high resolution melting real time PCR for mapping of filaria infection in domestic cats living in brugian filariosis-endemic areas. Veterinary Parasitology 2014; 201(1-2): 120-7.  
       
2013
  Maek-a-Nantawat W, Phonrat B, Bussaratid B, Nuamtanong S, Pakdee W, Dekumyoy P. Serum IgE and skin test using partially purified specific Gnathostoma spinigerum antigen by Immunoblot test detecting 24kD protein among patients with angioedema or eosinophilia. Journal of Allergy and Clinical Immunology 2013; 131(2): AB65  
       
    Yamane K, Yanagida T, Li TY, chen XW, Dekumyoy P, Waikagul J, Nkouawa A, Nakao M, Sako Y, Ito A, Sato H, Okamoto M. Genotypic relationships between Taenia saginata, Taenia Asiatic and their hybrids. Parasitology 2013 ; 140(3): 1595-601.  
       
2012
  Lapcharoen P, Komalamisra N, Rongsriyam Y, Wangsuphachart V, Dekumyoy P, Prachumsri J, Kajla MK, Paskewits SM. Investigations on the role of a lysozyme from the malaria vector Anopheles dirus during malaria parasite development. Developmental and Comparative Immunology 2012; 36(1): 104-11.  
       
    Tewawong N, Pitaksajjkul P, Dekumyoy P, Ekpo P, Ramasoota P. Mimotope identification using phage displayed random peptide libraries against monoclonal antibodies specific to house dust mite. Southeast Asian Jouranl of Tropica Medicine and Public 2012; 43(3): 614-23.  
       
    Bussaratid  V, Dekumyoy  P, Desakorn  V, Jaroensuk  N, Liebtawee  B, Pakdee  W, Wattanagoon  Y.  Predictive factors for Gnathostoma seropositivity in patients visiting the Gnathostomiasis clinic at the hospital for tropical diseases, Thailand during 2000-2005.  Southeast Asian J Trop Med Public Health 2010: 41; 1316-1321.  
       
2011
  Somthana K, Eshita Y, Kumsisri R, Dekumyoy P, Waikagul J, Kalambaheti T, Maneerat Y. Roles of partially purified antigens from Gnathostoma spinigerum larvae on antibody production by human B cell culture. Southerast Asian J Trop Med Public Health 2011; 42: 771-781.  
       
    Thaenkham U, Nuamtanong S, Vonghachack Y, Yoonuan T, Sanguankiat S, Dekumyoy P, Prommasack B, Kobayashi J, Waikagul J. Discovery of Opisthorchis lobatus (Trematoda: Opisthorchiidae): new recorded species of small liver flukes in the Greater Mekong Sub-region. J Parasitol 2011; 97(6): 1152-1158  
       
2010
  Bussaratid  V, Dekumyoy  P, Desakorn  V, Jaroensuk  N, Liebtawee  B, Pakdee  W, Wattanagoon  Y.  Predictive factors for Gnathostoma seropositivity in patients visiting the Gnathostomiasis clinic at the hospital for tropical diseases, Thailand during 2000-2005.  Southeast Asian J Trop Med Public Health 2010: 41; 1316-1321.  
       
    Kusolsuk  T, Kamonrattanakun  S, Wesanonthawech  A, Dekumyoy  P, Thaenkham  U, Yoonuan  T, Nuamtanong  S, Sa-nguankiat  S, Pubampen  S, Maipanich  W, Panitchakit  J, Marucci  G,    Pozio  E, Waikagul  J.  The second outbreak of trichinellosis caused by Trichinella papuae in    Thailand.  Transactions of the Royal Society of  Tropical Medicine and Hygiene  2010; 104:  433-437.  
       
    Pakdee W, Waikagul J, Kalambaheti T, Ito A, Dekumyoy  P.  ISO- electricfocusing of Bithynia snail antigens for IgG-and IgG1-4 - ELISA detection of human opisthorchiasis. Southeast Asian J  Trop Med Public Health 2010;  41(4): 813-820.  
       
    Riyong  D, Waikagul  J, Panasoponkul  C, Choochote  W, Ito  A, Dekumyoy  P.  Size and charge antigens of Dirofilaria immitis adult worm for IgG-ELISA diagnosis of bancroftian filariasis. Southeast Asian J Trop Med Pub Health 2010; 41: 285-297.  
       
    Sato  M, Pongvongsa  T, Sanguankiat  S, Yoonuan  T, Dekumyoy  P, Kalambaheti  T, Keomougkhoun  M, Phimmayoi  I, Boupha  B, Moji  K, Waikagul  J.  Copro-DNA diagnosis of Opisthorchis viverrini and Haplorchis taichui infection in an endemic area of LAO PDR.  Southeast Asian J Trop Med Public Health 2010; 41:28-35.  
       
    Thaenkham  U, Dekumyoy  P, Komalamisra  C, Sato  M, Dung  DT, Waikagul  J. Systematics of the subfamily Haplorchinae (Trematoda: Heterphyidae), based on nuclear Ribosomal DNA genes and ITS2 region.  Parasitology International 2010; 59:   460-465.  
       
    Vitta A, Yoshino TP, Kalambaheti T, Komalamisra C, Waikagul J, Ruangsittichai J,  Dekumyoy  P. Recombinant SMR-domain containing protein of Angiostrongylus cantonensis and its application  in immunoblot diagnosis  of human angiostrongyliasis.  Southeast Asian J Trop Med Public Health 2010; 41(4): 785-799.  
       
2009
  Dong ML, Xue RC, Jing SZ, Zhi BX, Nawa Y, Dekumyoy P. Short report: Case of gnathostomiasis in Beijing, China Am J Trop Med Hyg 2009; 80(2): 185-7.  
       
    Komalamisra C, Nuamtanong S, Dekumyoy P. Pila ampullacea and Pomacea canaliculata, as new paratenic hosts of Gnathostoma spinigerum. Southeast Asian J Trop Med Public Health 2009; 40: 243–246.  
       
    Kusolsuk T, Paiboon N, Pubampen S, Maipanich W, Dekumyoy P, Waikagul J. Anchitrema sanguineum (Digenea: Anchitrematidae) Accidentally Found during Collnoscopy of a Patient with Chronic Abdominal Pain: A Case Report. Korean J Parasitol 2009: 47(2): 167-170.  
       
    Li DM, Chen XR, Zhou JS, Xu ZB, Nawa Y, Dekumyoy P. Short Report: Case of Gnathostomiasis in Beijing, China. Am J Trop Med Hyg 2009; 80(2): 185-7.  
       
    Maretić T, Perović M, Adriana V, Lukas D, Dekumyoy P, Begovac J. Meningitis and radiculomyelitis caused by Angiostrongylus cantonensis EID 2009;15:996-8  
       
    Sato M, Thaenkham U, Dekumyoy P, Waikagul J. Discrimination of O. viverrini, C. sinensis, H.pumilio and H. taichui using nuclear DNA-based PCR targeting ribosomal DNA ITS regions. Acta Tropica 2009; 109: 81-83.  
       
    Strady C, Dekumyoy P, Clement-Rigolet M, Danis M, Bricaire F, Caumes E. Long-term follow-up of imported gnathostomiasis shows frequent treatment failure. Am J Trop Med Hyg 2009; 80(1): 33-5.  
       
2008
  Khumjui C, Choomkasien P, Dekumyoy P, Kusolsuk T, Kongkaew W, Chalamaat M, Jones JL. Outbreak of trichinellosis caused by Trichinella papuae, Thailand, 2008. EID 2008;14:1913-5.  
       
    Yoonuan T, Vanvanitchai Y, Dekumyoy P, Komalamisra C, Kojima S, Waikagul J. Paragonimiasis Prevalences in Saraburi Province, Thailand, Measured 20 years apart. Southeast Asian J Trop Med Puboic Health 2008; 39: 593-600.  
       
2006
  Develoux M, Dekumyoy P, Baygon E, Aractingi S. Gnathostomose d’importation contractee au Myanmar (Imported gnathostomiasis acquired in Myanmar) Medecine et maladies infectieuses 2006:36:340-2.  
       
    Eamsobhana P, Ongrotchanakun J, Yoolex A, Monkong N, Punthuprapasa P, Dekumyoy P. Multi-immunodot for rapid differential diagnosis of eosinophilic meningitis due to parasitic infections J Helminthology 2006;80:1-7.  
       
    Waikagul J, Dekumyoy P Anantaphuti MT. Taeniasis, cysticercosis and echinococcosis in Thailand. Parasitol Int. 2006;55:S175-80.  
       
    Waikagul J, Dekumyoy P, Yoonuan T, Praevanit R. Conjuntiva philophthalmosis: a case report in Thailand. Am J Trop Med Hyg 2006;74:848-9.  
       
2005
  Anantaphuti MT, Nuamtanong S, Dekumyoy P. Diagnostic value of IgG4 in gnathostomiasis. Trop Med and International Health 2005;10:1013-1021.  
       
    Dekumyoy P, Riyong D, Pakdee W, Waikagul J. Negative-ELISA using native and filtrated cystic fluid antigens to rule out cystic echinococcosis Southeast Asian JTrop Med Public Health. 2005;36(Suppl.):139-145.  
       
    Koga M, Nuamtanong S, Dekumyoy P, Yoonuan T, Maipanich W, Rojekettikhun W,Waikagul J. Host-finding behavior of Strongyloides stercoralis larvae to sodium cation, human serum, and sweat. Southeast Asian JTrop Med Public Health. 2005;36(Suppl.):93-98.  
       
    Lapcharoen P, Apiwathnasorn C, Komalamisra N, Dekumyoy P, Palakul K, Rongsriyam Y. Three indigenous medical Thai plants for control of Ades aegypti and Culex quinquefasciatus Southeast Asian JTrop Med Public Health. 2005; 36(Suppl.):167-175.  
       
    Ngarmamonpirat C, Waikagul J, Petmitr S, Dekumyoy P, Rojekettikhun W, Anantaphuti MT. Analysis of sequence variation in Gnathostoma spinigerum mitochondrial DNA by single-strand conformation polymorphism analysis and DNA sequence. Parasitol Int. 2005;54:65-8.  
       
    Nontasut P, Claesson BA, Dekumyoy P, Pakdee W, Chullawichit S. Double-dose ivermectin vs albendazole for the treatmen of gnathostomiasis. Southeast Asian JTrop Med Public Health. 2005;36:650-2.  
       
    Riyong D, Dekumyoy P, Panasoponkul C, Waikagul J. Detection of IgG antibodies of Brugian filariasis with crude male and female antigens of Dirofilaria immitis Southeast Asian JTrop Med Public Health. 2005;36(Suppl.):80-85.  
       
    Wathanakulpanich D, Waikagul J, Dekumyoy P, Muangkhum P, Praevanit R, Mongkhonmu S. Paragonimiasis in Nan Province , north Thailand. Southeast Asian JTrop Med Public Health. 2005;36:193-197.  
       
2004
  Dekumyoy P, Waikagul J, Vanijanonta S, Thaitungroj M, Nakao M, Sako Y, Watanabe S, Ito A. Cysticercosis: IgG-ELISA evaluations of peak1 antigen and <30 kDa antigen of delipidized extract of Taenia solium metacestodes. Southeast Asian JTrop Med Public Health. 2004;35:1-9.  
       
    Koga M, Sa-nguankiat S, Muennoo C, Pubumpen S, Nuamtanong S, Maipanich W, Rojekettikhun W, Dekumyoy P, Waikagul J. Chemotactic attraction of Necator hookworm filariform larvae to sodium chloride. Southeast Asian JTrop Med Public Health. 2004;35 (Suppl.):112-115.  
       
    Sawanyawisuth K, Tiamkao S, Kanpitaya J, Dekumyoy P, Jitpimolmard S. MR imaging findings in cerebrospinal gnathostomiasis. AJNR Am J Neuroradiol 2004;25:446-449.  
       
    Sawanyawisuth K, Tiamkao S, Nitinavakarn B, Dekumyoy P, Jitpimolmard S. MR imaging findings in cauda equina gnathostomiasis. AJNR Am J Neuroradiol 2004;26:39-42.  
       
    Xuan LT, Hoa PTL, Dekumyoy P, Van TTH, Mai VTC, Hoan NH, Khuong LH, Tu LX, Hien TV. Gnathostoma infection in South Vietnam. Southeast Asian JTrop Med Public Health .2004;35 (Suppl.):97-99.  
       
2003
  Menard A, Santos GD, Dekumyoy P, Rangue S, Delmont J, Danis M, Bricaire F, Caumes E. Imported cutaneous gnathostomiasis: report of five cases. Trans R Soc Trop Med Hyg2003;97:1-3  
       
    Moore DAJ, McCrodden J, Dekumyoy P, Chiodini PL. Gnathostomiasis: an emerging imported disease. Emerging Infectious Diseases 2003;9:647-650.  
       
2002
  Dekumyoy P, Somtana K, Jantanawiwat P, Nuamtanong S, Sa-nguankiat S, Nuchfaong S, Janyapoon K, Chindanond D. Improved antigens for IgG-ELISA diagnosis of strongyloidiasis. Southeast Asian JTrop Med Public Health. 2002;33:53-59  
       
    Waikagul J, Dekumyoy P, Chaichana K, Anantaphuti MT, Komalamisra C, Kitikoon V. Serodiagnosis of human opisthorchiasis using cocktail and electroeluted Bithynia snail, antigens Parasitology International 2002;51:237-247.  
       
    Wathanakulpanich D, Waikagul J, Dekumyoy P, Anantaphuti MT. Antigenic community between Opisthorchis viverrini adult worms and their intermediate hosts, Bithynia snails as a support for concomitant antigens. J Trop Med Parasitol2002;25: 17-25.  
       
2001
  Chandenier J, Husson J, Canaple S, Gondry-Jouet C, Dekumyoy P, Danis M, Riveau G, Hennequin C, Rosa A, Raccurt CP. Medullary gnathostomiasis in a white patient: use of immunodiagnosis and magnetic resonance imaging. Clinical Infectious Diseases 2001; 32:e154-7.  
     
  Parola P, Dekumyoy P, Delmont J, Brouqui P. Clinical picture: Gnathostomiasis. The Lancet 2001; 357: 31.  
     
  Vongpakorn M, Waikagul J, Dekumyoy P, Chompoochan T, Rojekittikhun, Pongponratn E. Comparison of ELISA and GPAT in diagnosis of Bovine fasciolosis using excretory-secretory antigen. J Trop Med Parasitol 2001; 24: 1-7.  
     
2000
  Dekumyoy P, Anantaphuti MT, Nuamtanong S, Wathanakulpanich D, Waikagul J, Danis M. Neurocysticercosis : utilizing the cystic fluid antigen from Taenia solium metacestodes for diagnosis by IgG-ELISA. Southeast Asian JTrop Med Public Health 2000; 31Suppl.1:21-5.  
     
  Dekumyoy P, Insun D, Waikagul J, Anantaphuti MT, Roungsriyaem Y. IgG-and IgG 4-detected antigens of Dirofilaria immitis adult worms for detection of Bancroftian filariasis by enzyme-linked immunoelectrotransfer blot technique. Southeast Asian JTrop Med Public Health2000; 31Suppl.:58-64.  
     
  Dekumyoy P, Komalamisra C, Nuamtanong S, Nacapunchai D, Sinnawong M, Shanaha P, Piyasatittam P. Angiostrongyliasis : analysis of antigens of Angiostrongyluscostaricensis adult worms versus IgG from infected patients with Angiostrongyluscantonensis.Southeast Asian JTrop Med Public Health 2000; 31Suppl.1:48-53.  
     
  Komalamisra C, Boonchuen S, Waikagul J, Dekumyoy P, Komalamisra N. Comparative studies on general proteins, isoenzyme and restriction endonuclease profiles of thai Paragonimus metacercariae. Southeast Asian JTrop Med Public Health 2000; 31Suppl.1:35-43.  
     
1999
  Eamsobhana P, Dekumyoy P, Waikagul J. Shared antigens between Parastrongylus cantonensis and Biomphalaria glabrata and their possible use in immunodiagnosis of human parastrongyliasis. Trop Biomed 1999;16:7-13.  
     
  Wongkamchai S, Mahakittikun V, Dekumyoy P, Onrotchanakun J. Immunoblotting and enzyme-linked immunosorbent assay for diagnosis of Toxoplasma infection in HIV Thai patients Southeast Asian JTrop Med Public Health 1999;30:580-2.  
     
1998
  Dekumyoy P, Vanijanonta S, Waikagul J, Sa-nguankiat S, Danis M. Utilizing the delipidized antigens of Taenia solium metacestodes for IgG-ELISA in the detection of neurocysticercosis. Southeast Asian JTrop Med Public Health 1998;29:572-8.  
     
  Dekumyoy P, Waikagul J, Eom KS. Human lung fluke (Paragonimus heterotremus): Differential diagnosis between Paragonimus heterotremus and Paragonimus westermani infections by EITB. Trop Med and International Health 1998; 3:52-6.  
     
  Wathanakulpanich D, Waikagul J, Dekumyoy P, Anantaphuti MT. Application of the gelatin particle indirect agglutination test in the serodiagnosis of human opisthorchiasis. Japanese Journal of Tropical Medicine and Hygiene 1998;26:5-10.  
     
1997
  Mahannop P, Anantaphuti MT, Dekumyoy P, Chunnoo V. Detection of serum IgG to human hookworm (Necator americanus ) and its reactive protein antigen. The Journal of Tropical Medicine and Parasitology 1997; 20:50-6.  
     
  Wathanakulpanich D, Waikagul J, Anantaphuti M.T., Dekumyoy P. Evaluation of Bithynia funiculata snail antigens by ELISA serodiagnosis of human opisthorchiasis. Southeast Asian JTrop Med Public Health 1997;28:593-8.  
     
1995
  Dekumyoy P, Setasuban P, Waikagul J, Yaemput S, Sa-nguankiat S. Human lung fluke (Paragonimus heterotremus): Differentiation of antigenic proteins of adult worms by enzyme–linked immunoelectrotransfer blot technique Southeast Asian JTrop Med Public Health 1995;26:434-8.  
     
  Setasuban P,Hiranyachattada P, Prachasitthisak Y, Pubumpen S, Rojekettikhun W, Dekumyoy P. Effects of cobalt-60 gamma radiation on Gnathostoma spinigerum larvae. INIS Atomindix 1995; 26(1).  
     
1994
  Yaemput S, Dekumyoy P, Visiadksuk K. The natural first intermediate host of Paragonimus siamensis (Miyazaki & Wukoff, 1964) in Thailand. Southeast Asian J TropMed Public Health 1994;25:284-90.  
     
1993
  Anantaphuti MT, Achawanitkun W, Sa-nguankiat S, Dekumyoy P, Nuamtanong S, Waikagul J, Tsuji M. Intensity of infection, worm expulsion and efficacy of multiple doses of Albendazole and Mebendazole against trichuriasis. Collected Paper on the Control of Soil -transmitted Helminthiasis, Volume V. The Asian Parasite Control Organization (APCO), December 1993:179-83.  
     
  Setasuban P, Dekumyoy P, Komalamisra C, Muennoo C, Pahuchon W. Albendazole (Zeben) in the treatment of trichuriasis in school children at Choomchon Wat Sumrong Primary School, Nakhon Sri Thammarat. Collected Paper on the Control of Soil-transmitted Helminthiasis, Volume V. The Asian Parasite Control Organizatio (APCO), December 1993: 165-7.  
     
1991
  Setasuban P, Jewjhangarnwanit S, Rojanakittikoon V, Yaemput S, Dekumyoy P, Akahane H, Kojima, S. Gnathostoma spp. with special reference to a new type of larvae found in Fluta alba. Emerging Problems in Food-borne Parasitic Zoonosis : Impact on Agriculture and Public Health, Proceedings of the 33rd SEAMEO-TROPMED Regional Seminar, Southeast Asian J Trop Med Public Health 1991;22:220-4.  
     
1989
  Nontasut P, Singhasivanon V, Prarinyanuparp V, Chiamratana B, Sanguankiat S, Dekumyoy P, Setasuban, P. Effect of single-dose mebendazole on Necator americanus Southeast Asian J Trop Med Public Health 1989; 20:237-42.  
     
1988
  Nopparatana C, Tapchaisri P, Setasuban P, Chaicumpa W, Dekumyoy P. Antibody responses in human Gnathostomiasis. Southeast Asian J Trop Med Public Health 1988;19:219-24.  
     
  Setasuban P, Sa-nguankiat S, Dekumyoy P, Chamrattana B, Komalamisra C, Hiranyachattada P, Rojckittikhun W. Studies on parasites and parasitic ova in fresh vegatables in Nakhon Sri Thammarat (Research note). Journal of Parasitology andTropical Medicine Association of Thailand 1988; 11:31-2.  
     
1986
  Tapchaisri P, Dekumyoy P, Asavanich A, Tharavanij S, Harinasuta T. Occurrence of a common epitope in circum-sporozoite proteins of Plasmodium falciparum isolated from different areas in Thailand. Southeast Asian J Trop Med Public Health 1986; 17:13-8.  
     
  Tapchaisri P, Dekumyoy P, Asavanich A, Tharavanij S, Harinasuta T. Species and stage specificities of circum -sporozoite protein of Plasmodium falciparum (Research note) Mosq Borne Dis Bull. 1986;2;67-8.  
     
1985
  Tapchaisri P, Dekumyoy P, Asavanich A, Chongsa-Nguan M, Tharavanij S, Harinasuta, T. Antibodies against circum -sporozoite proteins of Plasmodium falciparum induced by natural infection. Southeast Asian J Trop Med. Public Hlth. 1985;6:355-64.  
 
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