Current Research activities

Research

The department of Helminthology carries out research activities in basic and applied sciences in 4 main areas.

1.Diversity and Taxonomy
2.Biology and Epidemiology
3.Immunodiagnosis
4.Molecular Biology

Ongoing Research

Angiostrongyliasis

1.Angiostrongyliasis: partially purified antigens of Angiostrongylus cantonensis adult worms for diagnosis using immunoblot.
2.Angiostrongyliasis: potential fractionated antigens of Angiostrongylus cantonensis adult worms for diagnosis using ELISA.
3.Analysis of a protein expression from Angiostrongylus cantonensis DNA cloning for serodiagnosis of angiostrongyliasis.
4.Detection of IgG-subclass for serodiagnosis of angiostrongyliasis.

 

Cysticercosis and Taeniasis

1.Comparison of biochemical extracts preparations of Cysticercus cellulosae by SDS polyacrylamide gel electrophoresis and immunoblot technique.
2.mtDNA sequences of Taenia spp.
3.Molecular epidemiology of Taeniasis in Thailand

Echinococcosis

1.Mitochondrial DNA sequence of protoscoleces of Echinococcus cysts from four patients.
2.Serodiagnosis of suspected echino-coccosis cases using native, partially-purified, and DNA recombinant antigens.

 

Filariasis

-Rare or unrecognized evidence of human dirofilariasis in Thailand: possible immunoblot diagnosis of one Thai patient.

 

Gnathostomiasis

1.Immunoblot-diagnostic specificity for gnathostomiasis.
2.Prevalence of Gnathostoma spinigerum in cats and dogs in Buddhist Temples in Bangkok.

Opisthorchiasis

-Studies on the efficacy of Thai traditional herbal medicines in the treatment of opisthorchiasis in hamsters.

Paragonimiasis

1.32-33 kDa-eluted Paragonimus heterotremus antigen for serodiagnosis.
2.Molecular systematic of Paragonimus lung flukes and intestinal trematodes.
3.Studies on Paragonimus populations: morphology, enzymology, molecular biology and epidemiology aspects.

Soil-transmitted helminthiasis

1.Efficacy of high dose mebendazole against trichuriasis in adult patients.
2.Herbal medicinal effects on soil-transmitted helminthiasis.
3.Impact of deworming on anemic status of children and adolescence girls.
4.Relationship between behavior and soil-transmitted helminthiasis in seaman.

Toxocariasis

1.Evaluation of excretory-secretory and partially purified antigens of adult Toxocara canis against
2.Toxocariasis by ELISA and immunoblot.
3.Toxocara canis larval antigens for serodiagnosis of human toxocariasis.

 

Trichinellosis

1.Effect of trichinellosis on lipid peroxidation in rat
2.Trichinellosis papuae in Ban-Rai district, Uthaithani Province, Thailand

 

Other parasites

1.Diagnosis of liver and intestinal flukes by PCR.
2.Differential serodiagnosis between liver and intestinal trematodes.
3.Fish-borne trematodes in Thailand.
4.Helminthic infection in Tsunami-affected area: soil contamination and infection rates in the population.
5.Cross-sectional study of parasitic infections and enteric bacteria among food handlers and water sources in primary school and restaurants at Sai-yok district, Kanchanaburi Province.