| 2008 |
| |
| Genetic typing of the 56-kDa type-specific antigen gene of contemporary Orientia
tsutsugamushi isolates causing human scrub typhus at two sites in north-eastern and western Thailand. |
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| Blacksell, S. D., Luksameetanasan, R., Kalambaheti, T., Aukkanit, N., Paris, D. H., McGready, R.,
Nosten, F., Peacock, S. J., and Day, N. P. |
| |
| Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand
stuart@tropmedresac |
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| Abstract: Orientia tsutsugamushi is the causative agent of scrub typhus, a major cause of febrile
illness in the rural areas of Southeast Asia. Twenty-three strains of O. tsutsugamushi were isolated from patients with scrub typhus in north-east (Udorn
Thani province) and western Thailand (Tak province) between 2003 and 2005. The isolates were characterized by sequencing the entire ORF of the 56-
kDa-type-specific antigen gene, followed by phylogenetic analysis. The majority (15/23) of isolates clustered with the Karp-type strain, six with a Gilliam-
type strain and one each with the T |
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| Published in:FEMS Immunol.Med.Microbiol. 52[3], 335-342. 2008. |
