| 2008 |
| |
| Prevalence and sequence diversity of a factor required for actin-based motility in natural
populations of Burkholderia species. |
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| Sitthidet, C., Stevens, J. M., Chantratita, N., Currie, B. J., Peacock, S. J., Korbsrisate, S., and
Stevens, M. P. |
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| Department of Immunology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Pran-nok
Road, Bangkoknoi, Bangkok 10700, Thailand |
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| Abstract: Actin-based motility of the melioidosis pathogen Burkholderia pseudomallei requires
BimA. We report a high degree of conservation of bimA in 99 B. pseudomallei isolates from the area of endemicity. A geographically restricted subset of
B. pseudomallei isolates harbored a B. mallei-like bimA allele (12.1%), confounding a differential diagnostic test based on amplification of species-specific
bimA regions |
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| Published in:J.Clin.Microbiol. 46[7], 2418-2422. 2008. |