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Research
 
    Departments
     Department of Clinical Tropical Medicine      Department of Helminthology
     Department of Medical Entomology      Department of Microbiology and Immunology
     Department of Protozoology      Department of Social and Environmental Medicine
     Department of Tropical Hygiene      Department of Tropical Nutrition and Food Science
     Department of Tropical Pathology      Department of Tropical Pediatrics
     Department of Molecular Tropical Medicine and Genetics  
    Centers
     Rajanagarindra Tropical Disease International Centre      Kanchanaburi Tropical Disease Research Centre
 
Departments
Department of Clinical Tropical Medicine
  The Department of Clinical Tropical Medicine was established in 1960, with the founding of the Faculty of Tropical Medicine, to pursue research and training in tropical diseases prevalent in Thailand and thereby contribute to the advancement of knowledge and clinical care in tropical medicine. The Department has a long and proud history of contributions to clinical care and research, especially in malaria, AIDS, melioidosis, leptospirosis, scrub typhus, and avian influenza. The major focus for malaria is the search for complicated and uncomplicated multi-drug resistant falciparum malaria.
 
Combinations of various antimalarials have been evaluated, especially artesunate or artemether followed by mefloquine, which was found to be the drug of choice for an alternative treatment for multidrug-resistant malaria. The Department, as part of the Faculty, was appointed the WHO Collaborating Centre for Clinical Management of Malaria. Departmental staff have also actively performed various research and clinical trials in collaboration with the Ministry of Public Health and various national and international academic institutes, searching for a suitable AIDS vaccine for Thailand over the past 14 years. We are the only group to have conducted two efficacy trials involving rgp120 and vector-based HIV vaccines. Apart from their work on AIDS vaccines, the staff have also participated in multi-centre trials of Quadrivalent HPV vaccine for cervical cancer, which was licensed last year. Staff of the Department are actively involved with major clinical trials for the treatment of melioidosis, in close collaboration with various institutes, including Oxford University, Khon Kaen University, and other hospitals, such as Sappasithiprasong and Ubon Ratchathani hospitals. Antiviral drugs, using a variety of new dosages and regimens, have been tested for novel treatments for avian influenza. Over the past 20 years, more than 300 articles related to the above diseases have been published in international peer-reviewed journals.
 
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  Department of Helminthology
 
The mission of our department is teaching, training, research and services in the field of tropical diseases caused by medically important helminthes. The important role is teaching post graduate courses to medical doctors and health personnel from the SEAMEO member countries, as well as others from over the world. The Department carries out research activities in the basic and applied sciences in 4 main areas, include taxonomy and diversity of helminthes, biology and epidemiology, immunodiagnosis, and molecular biology.

Role of academic services, we established the immunodiagnosis unit for helminthic infections in
1987 in order to service on serological testing for some helminthic infections. Up to date, more than diagnosed 13,000 serum samples from all over the world have been tested in this unit. Moreover, we are proud to be one of the recommendation sites among many famous institutes for serodiagnosis of helminthic infections, particularly Cysticercosis, Gnathostoma and Angiostrongylus infections.

At present, the International Reference Centre for Food and Water Borne Parasitic Zoonoses is formulating for promotion of international networking on information and services exchange of parasitic zoonoses, identification and diagnosis.
 
 
  Department of Medical Entomology
  Study of insecticidal activity of several species of Thai herbal extracts for controlling mosquito vectors. The promising oil extracts that showed mosquito repellency, such as qinghao (Artemisia annus), “may chang” (Litsea cubeba), clove (Syzygium aromaticum), and “makaen” (Zanthoxylum limonella), have been formulated in the forms of cream or gel. The extract of “thong pun chang” ( Rhinacanthus nasutus), which provided high larvicidal activity, has been prepared as tablet form. A mosquito repellent formulation of mixture volatile oil and Artemisia annua, is now petty patent.
 
 
  Department of Microbiology and Immunology
  The Department of Microbiology and Immunology was established in 1966. The Department’s objective is focused on researches in medical science and educational programs, which relate to microbial pathogens and the host immune defenses, host-pathogen interaction and related fields; especially in malaria, leptospirosis, scrub typhus, and dengue fever, and the other pathogenic bacterial and viral infection. The Department has actively involved in teaching the students in the post graduate courses e.g. M.Sc. (Trop. Med.), Ph.D. (Trop. Med.), and D.T.M.& H.

Through this website, we hope to present an overview of our department, research activities and to inspire like-minded individuals to join us in our quest.
 
Department of Protozoology
  To respond to the Faculty’s Mission to be “ Asia’s Leader in Tropical Medicine” ,the Department of Protozoology is responsible for the Research-based Diagnostic Unit”. We, therefore, provide diagnostic techniques based on up-to-date research from enzyme to community level.
Department of Social and Environmental Medicine
  The Department supports the teaching-learning process of the Faculty by offering various postgraduate courses leading to the M. Sc. and Ph. D. in Tropical Medicine. With its focus on social medicine, environmental health and environmental toxicology, the Department integrated the concepts of health promotion and disaster management in some of the course syllabi for the first time in 2006 and plans for more coverage in the following years.

Research activities of the Department have expanded to cover both laboratory and field investigations in tropical diseases, such as malaria, dengue hemorrhagic fever, tuberculosis, leptospirosis as well as field surveys of snail intermediate hosts and water quality in Tsunami -
affected areas. These have brought the Department a number of revenue, i.e., government budget and research funds from various organizations such as World Health Organization (WHO), Thailand Research Fund (TRF), National Research Council of Thailand (NRCT), Universita Degli Studi Di Brescia, etc.

In addition to various kinds of laboratory investigation and other academic services, the Department, during the year 2007, offered a technical service to the SEAMEO TROPMED Network by taking part in conducting an external evaluation of the National Tuberculosis Control Programme of Lao PDR (under the Global Fund to Fight AIDS, Tuberculosis and Malaria-GFATM). Advices were also given to the Mekong River Commission Secretariat in conducting a transboundary risk assessment along the borders of Thai-Lao PDR and Vietnam-Cambodia and the Swiss National Centre for Competence in Research (NCCR). The Department also serves as primary contact of WHO Collaborating Centre for Environmental Management for Disease Vector Control in Sustainable Development (WHO CC No. 115).
 
Department of Tropical Hygiene
 
Graduate program and short course training on epidemiology and biostatistics combining with research studies ranging from molecular to field works which contribute to the advancement of knowledge-based health sciences are the core functions of the department. The department has been recognized for its varieties of research studies which have been published and widely cited locally and internationally including disease sequencing, clinical trial, geo-spatial epidemiology, community study as well as statistical modeling This is due the fact that faculty members and students have access to and utilize the well-equipped department laboratory and well-established cohorts in selected field study site to conduct their own research within their areas of interest.
Several international short training courses have been offering throughout the year including, for example, courses in biomedical informatics, geographical informatics and biostatistics. Besides the current graduate degree focusing mainly in tropical medicine epidemiology, the department is in the process of moving forward to offer courses in zoonotic epidemiology, public health informatics and global health arena.
Department of Tropical Nutrition and Food Science
  The Department of Tropical nutrition and Food Science was established in 1966, to teach and train postgraduate students, to conduct scientific research, and to provide laboratory services for nutritional disorders. The Department comprises 9 academic staff, 6 consultants, and 2 support staff. The staff teach postgraduate students in the international courses leading to the postgraduate Diploma in Tropical Medicine and Hygiene, Master of Science in Tropical Medicine and Doctor of Philosophy in Tropical Medicine, as well as short training courses, e.g., Food Safety and Food Control, Methods in Nutritional Assessment and Research, etc. They also conduct research in the nutritional sciences. In addition, they are responsible for technical services and the distribution of nutrition information to the community.
 
 
Department of Tropical Pathology
  Department of Tropical Pathology is one of the eleventh departments of the Faculty of Tropical Medicine, responsible for teaching, research and academic services. The department comprises 3 units: Diagnostic Pathology Unit, Electron Microscopy Unit and Tissue Culture and Immunocytochemistry Unit.

Training courses on tropical pathology, electron microscopy and histopathology are provided periodically upon request.

 
Research projects focus on histopathology, immunohistochemistry and ultrastructural studies of tropical diseases, especially malaria and other parasitic and infectious diseases have been performed in collaboration with many other organizations including international linkages : Department of Cellular Pathology, Oxford University,Liverpool School of Tropical Medicine, United Kingdom; Department of Immunology, The Wenner Gren Institute, Stockholm University, Sweden; and Department of Pathology, Faculty of Medicine, University of Sydney, Australia. (Current Research Activities)

Research highlight: For the first time we have visualized and measured sequestration in vivo, showing that, sequestration of parasitized erythrocytes in the microvasculature of vital organs is the central pathological feature of severe falciparum malaria.

Department of Tropical Pediatrics
  Department of Tropical Pediatrics has undergone considerable development on research, teaching, and services during the last 10 years. Collaboration with other research groups both nationally and internationally has been key feature of our activities. The new areas of research concern vaccine trials (including dengue vaccine, Japanese encephalitis vaccine and rabies vaccine) and pediatric infectious disease in the tropics (such as Dengue cohort study).
Centers
Rajanagarindra Tropical Disease International Centre , RTIC
  Rajanagarindra Tropical Disease International Centre , RTIC (1998) is located at Huai Muang Subdistrict , Suan Phueng District, Ratchaburi Province . Its activities, conducted and supervised by personnel from the Faculty, include research studies on epidemiology of malaria and various parasitic diseases; field training for students/ trainees; provision of health education and free health care services, especially malaria, to local people.

These activities are financially supported by the “Tropical Disease Trust Fund” which was initiated on 25 May 1998 under the Honorary Chairmanship of Her Royal Highness Princess Galayani Vadhana Krom Luang Naradhiwas Rajanagarindra who kindly donated an endowment
fund of 300,000 Baht. The Trust also received a fund of 50,000,000 Baht from the Government Lottery Office to facilitate its activities.

Up to date, the Tropical Disease Trust Fund has granted more than 20 research projects to the Faculty’s researchers. Moreover, on the 80 th Birthday Celebration of the Honorary Chairman in the year 2004, first-aid units were set up in eight schools of the Suan Phueng District.
Kanchanaburi Tropical Disease Research Centre
  Kanchanaburi Tropical Disease Research Centre
at Kanchanaburi Campus, Sai Yok District, Kanchanaburi Province, has been established as research station and field training centre for faculty staff, graduate students and medical students from the Collaborative Project to Increase Production of Rural Doctor, Mahidol University.
 
 
Last updated: January 7, 2011
 
 
 
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