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Research Projects |
The titles of current departmental research activities are as follows: |
1. |
A worldwide, phase I dose-escalating study of the safety, tolerability and immunogenicity of a three-dose regimen of the MRKAd5 HIV-1 gag Vaccine in healthy adults |
2. |
Imunogenicity and safety of quadrivalent HPV (Type 6,11,16,18) L1 virus-like particle (VLP) vaccine in 16-to 23 year-old women with an immunogenicity bridge between the HPV 16 component of the quadrivalent vaccine and the monovalent HPV 16 vaccine pilot manufacturing material and a study to evaluate the efficacy of quadrivalent HPV (Types 6, 11, 16, and 18) L1 virus-like particle (VLP) vaccine in reducing the incidence of HPV 6-11-and 18-related CIN, and HPV16 and 18 related external genital warts, VIN and VaIN, and HPV 16 and 18-related vulvar and vaginal cancer in 16-to 23 year-old women----The F.U.T.U.R.E. ( Females United to Unilaterally Reduce Endo/Ecto Cervical Cancer) Study |
3. |
Safety and immunogenicity studies of WRSd1, a live attenuated Shigella dysenteriae type 1 vaccine candidate in Thai adults |
4. |
Safety, immunogenicity, and efficacy of quadrivalent HPV (Types 6, 11, 16, 18) L1 virus-like particle (VLP) vaccine in mid-adult women - The FUTURE III Study |
5. |
A phase III trial of Aventis Pasteur live recombinant ALVAC-HIV (VCP1521) priming with Vaxgen gp 120 B/E (AIDSVAX B/E) boosting in HIV-uninfected Thai adults |
6. |
A study of Chantaleela herbal household remedy. 5 mg of Chantaleela was given to the patient every 4 hour for three days. Then the follow up was made on day 7 and day 14. |
7. |
Early Physician Experience Program of Darunavir in treatment experienced patients with limited to treatment options. |
8. |
Early Access of MK-0518 in combination with an optimized background antiretroviral therapy (OBT) in highly treatment experienced HIV-1 infected patients with limited to no treatment options. |
9. |
A Retrospective Study to Establish a Historical Database on the Efficacy of Standard Antifungal Therapy in Patients with Invasive Fungal Infection. |
10. |
Effect of drug accumulation in the neurotoxicity of artemether, dosing regimens with variable drug-free intervals in a mouse model |
11. |
Observational probe study of in vitro immune response parameters to candidate HIV-1 vaccine antigens among subjects from Thailand |
12. |
Neuropathological toxicity of artemisinin derivatives in a mouse model |
13. |
Development of field methods and investigators of the molecular basis of sulfonamide resistance in Plasmodium vivax |
14. |
Novel point mutations in the dihydrofolate reductase gene of Plasmodium vivax: evidence for sequential selection by drug pressure |
15. |
Asexual and sexual stage antimalarial activities of artesunate and primaquine in falciparum malaria |
16. |
Research and development for Thai people living at Thai-Myanmar border to free from tropical diseases |
17. |
Research and development on drugs and diagnostic tools for diagnosis and treatment of tropical diseases in Thailand |
18. |
Liver megaproject Phase 1: from basic research to education science and applied technology in clinical study |
19. |
A two-stage, phase II study to evaluate the safety and efficacy of CKBM-A01 in treating HIV patients in Thailand |
20. |
A comparison of doxycycline plus trimethoprim-sulphamethoxazole versus trimethoprim-sulphamethoxazole as maintenance therapy for melioidosis, a multicentre trial |
21. |
A randomized double blinded comparison of ceftazidime and meropenem in severe melioidosis, a multicentre trial |
22. |
Measurement of Anogenital Wart Burden and Cost of Illnesses in Thailand |
23. |
Measuring Herpes Zoster and Post-Herpetic Neuralgia Associated Burden of Illness and Health Care Utilcation and Costs in Thailand |
24. |
A Randomized, International, Double-Blinded (With In-House Blinding), Controlled With GARDASITM, Dose-Ranging, Tolerability, Immunogenicity, and Efficacy Study of a Multivalent Human Papillomavirus (HPV) L1 Virus-Like Particle (VLP) Vaccine Administered to 16- to 26-Year-Old Women |
25. |
Rabies exposure risk among foreign backpackers from non-ASEAN countries traveling in Southeast Asia |
26. |
The Research Project for Technology Transfer of Chronic Lymphede Treatment Targeting at Medical, Public Health, and Community Personnel in Thailand Southern Border Regions |
27. |
Study to evaluate a treatment guideline of twisting tourniquet technique with chronic lymphedema |
28. |
Evaluation of genetic susceptibility to meliodosis |
29. |
Abnormalities of coagulation and the immune response in diabetic patients with melioidosis |
30. |
A cross-sectional study to screen for and generate broadly neutralizing monoclonal antibodies from HIV infected individuals |
31. |
A phaseIV,multi-center, randomized, double blind, placebo controlled study to evaluate the safety of daily inhaled Zanamivir 10 mg versus placebo and daily oral Oseltamivir 75 mg versus placebo for influenza prophylaxis in healthy volunteers for 16 weeks |
32. |
Cell derived microparticles in malaria infection |
33. |
Effect of primaquine and its metabolite on the infectivity Of P. falciparum gametocyte |
34. |
Effect of serum lipid concentration on the efficacy of lumefantrine against falciparum malaria: in vitro |
35. |
Rapid dignosis of Leptospirosis by loop-mediated isothermal amplification Development of molecular technique for evaluation of Mefloquine resistance in Plasmodium falciparum in Asia |
36. |
VNTR Typing for Plasmodium falciparum and Plasmodium vivax |
37. |
Molecular characterisation of drug resistance in the human malarias |
38. |
Comparison of the safety and efficacy of a Unique Intravenous Iron Preparation (VIT-45)versus oral iron in the treatment of Anemia in non-dialysis dependent chronic kidney diseases |
39. |
Pharmacologic study of Oseltamivir in healthy volunteers |
40. |
Early access of MK-0518 in combination with an optimized background antiretroviral therapy (OBT) in highly treatment experienced HIV-1 infected patients with limited to no treatment options |
41. |
Bioequivalence study of 4 mg Perindopril tablets preparations in healthy Thai male volunteers |
42. |
In Vivo bioequivalence study of 160 mg Fenofibrate film-coated tablet preparation in healthy Thai male volunteers |
43. |
Phase 1, open-label study to evaluate potential pharmacokinetic interactions between orally-administered Oseltamivir and Intravenous Zanamivir in healthy Thai adult subjects |
44. |
A phase III, randomized, non-inferiority trial, to assess the efficacy and safety of dihydroartemisinin + piperaquine (DHA+PPQ, Artekin) in comparison with Artesunate+Mefloquine (AS+MQ) in patients affected by acute, uncomplicated Plasmodium falciparum malaria |
45. |
Pathology of mouse vital organs after injection with artemisinin derivatives |
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Last updated: May 13, 2009 |