{"id":788,"date":"2024-09-19T04:03:41","date_gmt":"2024-09-19T04:03:41","guid":{"rendered":"http:\/\/10.11.101.25\/wordpress\/vivax\/?p=788"},"modified":"2025-06-30T07:20:24","modified_gmt":"2025-06-30T07:20:24","slug":"g6pd","status":"publish","type":"post","link":"http:\/\/10.11.101.25\/wordpress\/vivax\/2024\/09\/19\/g6pd\/","title":{"rendered":"G6PD"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"788\" class=\"elementor elementor-788\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ec8e0c9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ec8e0c9\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4b4b0b5\" data-id=\"4b4b0b5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f32c5aa elementor-widget elementor-widget-heading\" data-id=\"f32c5aa\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/mahidolvivax.com\/en-US\/research-areas\">\u00ab Research Areas<\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-23f6e13 elementor-widget elementor-widget-heading\" data-id=\"23f6e13\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">G6PD<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fff710d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fff710d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0fe6240\" data-id=\"0fe6240\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4df4e73 elementor-widget elementor-widget-image\" data-id=\"4df4e73\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-content\/uploads\/sites\/5\/2024\/09\/Research_are_G6PD-1024x1024.jpg\" class=\"attachment-large size-large wp-image-789\" alt=\"\" srcset=\"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-content\/uploads\/sites\/5\/2024\/09\/Research_are_G6PD-1024x1024.jpg 1024w, http:\/\/10.11.101.25\/wordpress\/vivax\/wp-content\/uploads\/sites\/5\/2024\/09\/Research_are_G6PD-300x300.jpg 300w, http:\/\/10.11.101.25\/wordpress\/vivax\/wp-content\/uploads\/sites\/5\/2024\/09\/Research_are_G6PD-150x150.jpg 150w, http:\/\/10.11.101.25\/wordpress\/vivax\/wp-content\/uploads\/sites\/5\/2024\/09\/Research_are_G6PD-768x768.jpg 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0705092 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0705092\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-bee1f85\" data-id=\"bee1f85\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0852216 elementor-widget elementor-widget-text-editor\" data-id=\"0852216\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Over the past decade, malaria incidence has steadily declined in various parts of the worlds. The resilience of P. vivax relative to P. falciparum against malaria controls can be attributed, at least partially, to the parasite\u2019s ability to remain dormant as hypnozoites in the host\u2019s liver. Primaquine is an effective drug to treat hypnozoite and has been included in the anti-malarial drug regimen in most of the countries. Primaquine, and other 8-aminoquinolone drugs, can induce severe hemolysis in malaria patients who deficient in glucose-6-phosphate dehydrogenase (G6PD) enzyme activity. Female heterozygous G6PD deficiency is always missed by qualitative G6PD testing. Providing the primaquine to heterozygous G6PD malaria infected individual can potentially causing significant morbidity and diminish the impact of this drug. Studying G6PD deficiency especially in female heterozygous in the context of anti-malarial therapy and malaria elimination will support safe use of 8-aminoquinoline drugs for radical cure that will enable access to effective, life-saving therapy.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-558f438 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"558f438\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"aux-parallax-section elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a3dfa32\" data-id=\"a3dfa32\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d80ce85 elementor-widget elementor-widget-accordion\" data-id=\"d80ce85\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-2261\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-2261\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">On-going Project<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2261\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-2261\"><h5>\u00a0<\/h5><h5><a class=\"list_props_grid__link\" href=\"https:\/\/mahidolvivax.com\/en-US\/research\/projects\/the-comprehensive-study-on-the-effect-of-primaquine-treatment-in-p-vivax\">The comprehensive study on the effect of primaquine treatment in P. vivax infected G6PD deficient individuals and the prevalence of G6PD deficiency in malaria exposed population<\/a><\/h5><p>\u00a0 \u00a0 \u00a0\u00a0<img decoding=\"async\" class=\"alignnone wp-image-833\" src=\"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-content\/uploads\/sites\/5\/2024\/09\/NIH.jpg\" alt=\"\" width=\"200\" height=\"151\" srcset=\"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-content\/uploads\/sites\/5\/2024\/09\/NIH.jpg 1533w, http:\/\/10.11.101.25\/wordpress\/vivax\/wp-content\/uploads\/sites\/5\/2024\/09\/NIH-200x151.jpg 200w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/><\/p><div class=\"src-styles----single-story-module---topics_section---3EKaZ\" data-reactid=\"68\"><h4 class=\"src-styles----single-story-module---project_h2---1D6VI\" data-reactid=\"69\"><span style=\"text-decoration: underline;\">Topic of research<\/span><\/h4><p>International Laboratory Installation and Collaborative Research on Neglected Tropical and Vector-borne Diseases.<\/p><\/div><div class=\"src-styles----single-story-module---outcome_section---2K3EV\" data-reactid=\"71\"><h4 class=\"src-styles----single-story-module---project_h2---1D6VI\" data-reactid=\"72\"><span style=\"text-decoration: underline;\">Outcome<\/span><\/h4><p>Studying G6PD deficiency especially in female heterozygous in the context of anti-malarial therapy and malaria elimination will support safe use of 8-aminoquinoline drugs for radical cure that will enable access to effective, life-saving therapy.<\/p><\/div><div class=\"col-12 src-components-SocialMedia----SocialMedia-module---social_media_section---IzEcd\" data-reactid=\"74\"><h4 data-reactid=\"104\"><span style=\"text-decoration: underline;\">Key Information<\/span><\/h4><ul data-reactid=\"105\"><li data-reactid=\"106\"><h5 data-reactid=\"107\">Key MVRU Researchers:<\/h5><ul class=\"src-styles----single-story-module---researchers---1mWI6\" data-reactid=\"108\"><li data-reactid=\"109\"><a href=\"http:\/\/10.11.101.25\/wordpress\/vivax\/wanlapa-roobsoong\/\" data-reactid=\"110\">Dr.\u00a0Wanlapa Roobsoong<\/a><\/li><li data-reactid=\"114\"><a href=\"http:\/\/10.11.101.25\/wordpress\/vivax\/jetsumon-sattabongkot-prachumsri\/\" data-reactid=\"115\">Dr.\u00a0Jetsumon Sattabongkot Prachumsri<\/a><\/li><li data-reactid=\"119\"><a href=\"http:\/\/10.11.101.25\/wordpress\/vivax\/wang-nguitragool\/\" data-reactid=\"120\">Assoc. Prof. Dr.\u00a0Wang Nguitragool<\/a><\/li><\/ul><\/li><li data-reactid=\"124\"><h5 data-reactid=\"125\">Project Status:<\/h5><p data-reactid=\"126\">On-going<\/p><\/li><li data-reactid=\"127\"><h5 data-reactid=\"128\">Funded by:<\/h5><ul data-reactid=\"129\"><li data-reactid=\"130\">Korean national institute of health<\/li><li data-reactid=\"131\">National institute of Allergy and infectious diseases<\/li><\/ul><\/li><li data-reactid=\"132\"><h5 data-reactid=\"133\">In collaboration with:<\/h5><ul data-reactid=\"134\"><li data-reactid=\"135\">Liwang Cui,\u00a0Professor,\u00a0University of South Florida<\/li><\/ul><\/li><\/ul><\/div><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u00ab Research Areas G6PD Over the past decade, malaria incidence has steadily declined in various parts of the worlds. The resilience of P. vivax relative to P. falciparum against malaria controls can be attributed, at least partially, to the parasite\u2019s ability to remain dormant as hypnozoites in the host\u2019s liver. Primaquine is an effective drug [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":789,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"_links":{"self":[{"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/posts\/788"}],"collection":[{"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/comments?post=788"}],"version-history":[{"count":28,"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/posts\/788\/revisions"}],"predecessor-version":[{"id":2802,"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/posts\/788\/revisions\/2802"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/media\/789"}],"wp:attachment":[{"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/media?parent=788"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/categories?post=788"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/10.11.101.25\/wordpress\/vivax\/wp-json\/wp\/v2\/tags?post=788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}