Featured Projects
  • งานปาฐกถา ศรชัย
  • malaria


          Clinical Malaria Research Unit was established in late 2013 and is located on the 2nd floor of the Sornchai Looareesuwan Building (Eastern side), Faculty of Tropical Medicine to support research activities in the Faculty of Tropical Medicine. The research activities of the unit is focused on malaria disease mainly in Clinical aspect both hospital based and field based researchs with the aims; to determine the patho-physiogenesis in severe malaria, to investigate the new malaria treatment including adjuvant therapies, to determine the safety and efficacy for malaria treatment, etc. The unit has collaboration with Phop-Phra Hospital, Tak and Suan-Phung Hospital as well as The Rajanagarindra Tropical Disease International Centre (RTIC), Ratchaburee to study in the field works.
          We also collaborated with Department of Radiology, Ramathibodi-Hospital, Faculty of Medicine at Ramathibodi Hospital; Department of Pathobiology, Faculty of Science; Department of Pharmacology, Faculty of Allied Health Science, Thammasat University, Thailand; Bureau of Vector Borne Disease; Department of Medical Science, Ministry of Public Health, Thailand; Department of Immunology and Medicine, USAMC-AFRIMS, Thailand; (National Center for Global Health and Medicine, Japan) and Department of Pediatrics, Columbia University, U.S.A., and McLaughlin Center for Molecular Medicine, University of Toronto, Canada.

Current activities

          The mission of unit has served the mission of the Faculty of Tropical Medicine to pursue the mission in three major TropMed Strategies, Teaching Excellence, Research Excellence and Outstanding Clinical Outcome. The details of each activity are showed as follows:
Teaching Excellence:
          Unit’s staff has involved in the teaching activity of the Mahidol-Bangkok School of Tropical Medicine both in-house lectures and field works, particularly in 8 courses for Graduate and Diploma students of Faculty of Tropical Medicine as listed below:
Postgraduate(International) Program
          • Master of Science in Tropical Medicine, M.Sc. (Trop. Med.)
          • Doctor of Philosophy in Tropical Medicine, Ph.D. (Trop. Med.)
          • Master in Clinical Tropical Medicine (M.C.T.M.)
          • Master in Clinical Tropical Medicine (M.C.T.M.in Tropical Pediatrics)
          • Doctor of Philosophy in Clinical Tropical Medicine, Ph.D. (Clin. Trop. Med.)
          • Graduate Diploma in Tropical Medicine & Hygiene (D.T.M.& H.)
          • Master of Science School Health (M.Sc. SH)
          • Master of Science in Biomedical and Health Informatics (M.Sc.(BHI))
          • Diploma in Biomedical and Health Informatics (D.B.H.I.)
          • Residency training in Travel Medicine
Undergraduate Program
          • M.D. : Collaborative Project to Produce Rural Doctors (CPPRD)
The extra courses as listed below:
          • Other courses of Faculty of Tropical Medicine, e.g., Medical students, Nurse assistant students.
          • Training, Research fellow, Study visit of interns, students, researchers and other staffs from Thailand and foreign countries.
Research Excellence:
          Antimalarial drug trials, both efficacy and safety aspects, are mainly conducted. We are also studying on the patho-physiogenesis in severe malaria.
The current studied topics are
          • New combination therapies for malaria
          • Malaria field studies on efficacy and tolerability of antimalarial drug
          • Hematology profiles of malaria
          • Pathogenesis of severe malaria in Thailand
Medical Care Services
          Medical care service is one of the main functions of the unit. Our medical staffs have involved in activities of Bangkok Hospital for Tropical Diseases (both in-house works and field works).



Clinical Malaria Research Unit

Professor Srivicha Krudsood

Head of Unit & Project PI

E-mail: srivicha.kru@mahidol.ac.th
Tel: 66-2-354-9159, 66-2-643-5589-90

Professor Polrat Wilairatana

Project Co-PI

E-mail: polrat.wil@mahidol.ac.th
Tel: 66-2-354-9159

Assistant Professor Noppadon Tangpukdee

Project Investigator

E-mail: noppadon.tan@mahidol.ac.th
Tel: 66-2-354-9159, 66-2-643-5589-90
Ext. 110


Miss Kobsiri Chalermrut

Senior Project Nurse

E-mail: kobsiri.cha@mahidol.ac.th
Tel: 66-2-354-9159, 66-2-643-5589-90 Ext. 107

Mrs. Siripun Srivilairit

Project Nurse

E-mail: tmsvl@windowslive.com
Tel: 66-2-354-9159, 66-2-643-5589-90 Ext. 108

Miss Nanthaporn Phophak

Project Nurse

E-mail: nanthaporn.pho@mahidol.ac.th
Tel: 66-2-354-9159, 66-2-643-5589-90 Ext. 108


Mr. Sorose Pengruksa

Senior Project Co-ordinator

E-mail: sorose.pen@mahidol.ac.th
Tel: 66-2-354-9159, 66-2-643-5589-90 Ext. 106

Mrs. Suntaree Pengruksa

Secretary & Project Co-ordinator

E-mail: suntaree.pen@mahidol.ac.th
Tel: 66-2-354-9159, 66-2-643-5589-90

Mrs. Apaipun Poo-ngoen

Data entry co-ordinator

E-mail: apipun.poo@mahidol.ac.th
Tel: 66-2-354-9159, 66-2-643-5589-90 Ext. 112


Miss Nutcha Suwannate

Data entry co-ordinator

E-mail: nutcha.suw@mahidol.ac.th            Tel: 66-2-354-9159

Mrs. Ubon Satainchok

Senior General administrator

Tel: 66-2-354-9159, 66-2-643-5589-90 Ext. 104

Mrs. Laor Boontana

General administrator

Tel: 66-2-354-9159, 66-2-643-5589-90 Ext. 104


Mr. Amnuay Neamhom

Field co-ordinator

Tel: 66-2-354-9159, 66-2-643-5589-90

Clinical Malaria Research Unit, Faculty of Tropical Medicine, Mahidol University.
420/6 Rajvithi Road, Bangkok 10400.
Telephone: 66-2-354-9159 Fax: 66-2-354-9158



  • Osorio L, Carter N, Arthur P, Bancone G, Gopalan S, Gupta SK, Noedl H, Kochar SK, Kochar DK, Krudsood S, Lacerda MV, Llanos-Cuentas A, Rueangweerayut R, Srinivasan R, Treiber M, Möhrle JJ, Green J. Performance of BinaxNOW G6PD Deficiency Point-of-Care Diagnostic in P. vivax-Infected Subjects. Am J Trop Med Hyg. 2015 Jan 7;92(1):22-7.



  • Kashino W, Piyaphanee W, Kittitrakul C, Tangpukdee N, Sibunruang S, Lawpoolsri S, Yamashita H, Muangnoicharoen S, Silachamroon U, Tantawichien T. Incidence of potential rabies exposure among Japanese expatriates and travelers in Thailand. J Travel Med. 2014 Jul-Aug;21(4):240-7.

  • Laothamatas J, Sammet CL, Golay X, Van Cauteren M, Lekprasert V, Tangpukdee N, Krudsood S, Leowattana W, Wilairatana P, Swaminathan SV, DeLaPaz RL, Brown TR, Looareesuwan S, Brittenham GM. Transient lesion in the splenium of the corpus callosum in acute uncomplicated falciparum malaria. Am J Trop Med Hyg. 2014 Jun;90(6):1117-23.

  • Llanos-Cuentas A, Lacerda MV, Rueangweerayut R, Krudsood S, Gupta SK, Kochar SK, Arthur P, Chuenchom N, Möhrle JJ, Duparc S, Ugwuegbulam C, Kleim JP, Carter N, Green JA, Kellam L. Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study. Lancet. 2014 Mar 22;383(9922):1049-58.

  • Tangteerawatana P, Krudsood S, Kanchanakhan N, Troye-Blomberg M, Khusmith S. Low monocyte to neutrophil ratio in peripheral blood associated with disease complication in primary Plasmodium falciparum infection. Southeast Asian J Trop Med Public Health. 2014 May;45(3):517-30.



  • Chotivanich K, Udomsangpetch R, Suwanarusk R, Pukrittayakamee S, Wilairatana P, Beeson JG, Day NP, White NJ. Plasmodium vivax adherence to placental glycosaminoglycans. PLoS One. 2012;7(4):e34509.

  • Katakai Y, Komaki-Yasuda K, Tangpukdee N, Wilairatana P, Krudsood S, Kano S. Evaluation of the NOW Malaria Immunochromatographic Test for Quantitative Diagnosis of Falciparum and Vivax Malaria Parasite Density. Trop Med Health. 2011 Dec;39(4):105-8.

  • Tangpukdee N, Elshiekh SB, Phumratanaprapin W, Krudsood S, Wilairatana P. Factors associated with acute renal failure in falciparum malaria infected patients. Southeast Asian J Trop Med Public Health. 2011 Nov;42(6):1305-12.

  • Tangpukdee N, Krudsood S, Kano S, Wilairatana P. Falciparum malaria parasitemia index for predicting severe malaria. Int J Lab Hematol. 2012 Jun;34(3):320-7

  • Adhikari B, Tangpukdee N, Krudsood S, Wilairatana P. Factors associated with cerebral malaria. Southeast Asian J Trop Med Public Health. 2013 Nov;44(6):941-9.

  • Arnold BJ, Tangpukdee N, Krudsood S, Wilairatana P. Risk factors of shock in severe falciparum malaria. Southeast Asian J Trop Med Public Health. 2013 Jul 4;44(4):541-50.

  • Aung MN, Leowattana W, Win KN, Tangpukdee N, Muangnoicharoen S. Chronic hepatitis B prognostic markers other than pre-treatment viral load predicted composite treatment outcome. J Infect Dev Ctries. 2013 Jul 15;7(7):541-9.

  • Kaehler N, Piyaphanee W, Kittitrakul C, Kyi YP, Adhikari B, Sibunruang S, Jearraksuwan S, Tangpukdee N, Silachamroon U, Tantawichien T. Sexual behavior of foreign backpackers in the Khao San Road area, Bangkok. Southeast Asian J Trop Med Public Health. 2013 Jul 4;44(4):690-6.

  • Viputtigul K, Tungpukdee N, Ruangareerate T, Luplertlop N, Wilairatana P, Gaywee J, Krudsood S. C-terminal polymorphism of Plasmodium falciparium merozoite surface protein-1 (MSP-1) from Tak Province, Thailand. Southeast Asian J Trop Med Public Health. 2013 Jan;44(1):1-12.

  • Wilairatana P, Tangpukdee N, Krudsood S. Definition of hyperparasitemia in severe falciparum malaria should be updated. Asian Pac J Trop Biomed. 2013 Jul;3(7):586. doi: 10.1016/S2221-1691(13)60119-7.

  • Wilairatana P, Tangpukdee N, Krudsood S. Definition of hyperparasitemia in severe falciparum malaria should be updated. Asian Pac J Trop Biomed. 2013 Jul;3(7):586.

  • Tangpukdee N, Krudsood S, Wilairatana P, Schizontemia as an indicator of severe malaria. Southeast Asian J Trop Med Public Health. 2013 Sep;44(5):740 -43.