Name: Dr.Kamolchanok Claire Chewapreecha
ชื่อ-สกุล: อ.ดร.กมลชนก ชีวะปรีชา
Position: Lecturer
Department: Clinical Tropical Medicine
Cagape CMS, Seng R, Saiprom N, Tandhavanant S, Chewapreecha C, Boonyuen U, West TE, Chantratita N. Genetic variation, structural analysis, and virulence implications of BimA and BimC in clinical isolates of Burkholderia pseudomallei in Thailand. Sci Rep. 2024 Oct 23;14(1):24966. doi: 10.1038/s41598-024-74922-3.
Seng R, Chomkatekaew C, Tandhavanant S, Saiprom N, Phunpang R, Thaipadungpanit J, Batty EM, Day NPJ, Chantratita W, West TE, Thomson NR, Parkhill J, Chewapreecha C, Chantratita N. Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in Northeast Thailand. Nat Commun. 2024 Jul 7;15(1):5699. doi: 10.1038/s41467-024-50067-9.
Wongprommoon A, Chomkatekaew C, Chewapreecha C. Monitoring pathogens in wastewater. Nat Rev Microbiol. 2024 May;22(5):261. doi: 10.1038/s41579-024-01033-1.
Tantirat P, Chantarawichian Y, Taweewigyakarn P, Kripattanapong S, Jitpeera C, Doungngern P, Phiancharoen C, Tangwangvivat R, Hinjoy S, Sujariyakul A, Amornchai P, Wongsuvan G, Hantakun V, Wuthiekanun V, Thaipadungpanit J, Thomson NR, Dance DAB, Chewapreecha C, Batty EM, Limmathurotsakul D. Melioidosis in Patients with COVID-19 Exposed to Contaminated Tap Water, Thailand, 2021. Emerg Infect Dis. 2024 Apr;30(4):791-794. doi: 10.3201/eid3004.231476.
Pakdeerat S, Boonklang P, Angchagun K, Chomkatekaew C, Apichaidejudom N, Dokket Y, Faosap A, Wongsuwan G, Wuthiekanun V, Aramrueung P, Khamnoi P, Thananchai H, Siriboon S, Chamnan P, Peacock SJ, Day NPJ, Thomson NR, Uttamapinant C, Wongpalee SP, Chewapreecha C. Benchmarking CRISPR-BP34 for point-of-care melioidosis detection in low-income and middle-income countries: a molecular diagnostics study. Lancet Microbe. 2024 Apr;5(4):e379-e389. doi: 10.1016/S2666-5247(23)00378-6.
Seng R, Chomkatekaew C, Tandhavanant S, Saiprom N, Phunpang R, Thaipadungpanit J, Batty EM, Day NP, Chantratita W, West TE, Thomson NR, Parkhill J, Chewapreecha C, Chantratita N. Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in northeast Thailand. bioRxiv [Preprint]. 2023 Dec 10:2023.06.02.543359. doi: 10.1101/2023.06.02.543359.
Angchagun K, Boonklang P, Chomkatekaew C, Pakdeerat S, Wongsuwan G, Amornchai P, Wuthiekanun V, Panapipat S, Ngernseng T, Waithira N, Walton S, Limmathurotsakul D, Surawong A, Siriboon S, Chamnan P, Chantratita N, Dunachie S, Corander J, Davenport EE, Knight J, Parkhill J, Peacock SJ, Thomson NR, Day NPJ, Chewapreecha C. BurkHostGEN: a study protocol for evaluating variations in the Burkholderia pseudomallei and host genomes associated with melioidosis infection. Wellcome Open Res. 2023 Nov 2;8:347. doi: 10.12688/wellcomeopenres.19809.2.
Fen SHY, Tandhavanant S, Phunpang R, Ekchariyawat P, Saiprom N, Chewapreecha C, Seng R, Thiansukhon E, Morakot C, Sangsa N, Chayangsu S, Chuananont S, Tanwisaid K, Silakun W, Buasi N, Chaisuksant S, Hompleum T, Chetchotisakd P, Day NPJ, Chantratita W, Lertmemongkolchai G, West TE, Chantratita N. Antibiotic susceptibility of clinical Burkholderia pseudomallei isolates in northeast Thailand during 2015-2018 and the genomic characterization of β-lactam-resistant isolates. Antimicrob Agents Chemother. 2023 May 1;95(5):e02230-20. doi: 10.1128/AAC.02230-20.
Patchsung M, Homchan A, Aphicho K, Suraritdechachai S, Wanitchanon T, Pattama A, Sappakhaw K, Meesawat P, Wongsatit T, Athipanyasilp A, Jantarug K, Athipanyasilp N, Buahom J, Visanpattanasin S, Niljianskul N, Chaiyen P, Tinikul R, Wichukchinda N, Mahasirimongkol S, Sirijatuphat R, Angkasekwinai N, Crone MA, Freemont PS, Joung J, Ladha A, Abudayyeh O, Gootenberg J, Zhang F, Chewapreecha C, Chanarat S, Horthongkham N, Pakotiprapha D, Uttamapinant C. A Multiplexed Cas13-Based Assay with Point-of-Care Attributes for Simultaneous COVID-19 Diagnosis and Variant Surveillance. CRISPR J. 2023 Apr;6(2):99-115. doi: 10.1089/crispr.2022.0048.
Seng R, Phunpang R, Saiprom N, Dulsuk A, Chewapreecha C, Thaipadungpanit J, Batty EM, Chantratita W, West TE, Chantratita N. Phenotypic and genetic alterations of Burkholderia pseudomallei in patients during relapse and persistent infections. Front Microbiol. 2023 Feb 6;14:1103297. doi: 10.3389/fmicb.2023.1103297.
Tonkin-Hill G, Ling C, Chaguza C, Salter SJ, Hinfonthong P, Nikolaou E, Tate N, Pastusiak A, Turner C, Chewapreecha C, Frost SDW, Corander J, Croucher NJ, Turner P, Bentley SD. Pneumococcal within-host diversity during colonization, transmission and treatment. Nat Microbiol. 2022 Nov;7(11):1791-1804. doi: 10.1038/s41564-022-01238-1.
Wongpalee SP, Thananchai H, Chewapreecha C, Roslund HB, Chomkatekaew C, Tananupak W, Boonklang P, Pakdeerat S, Seng R, Chantratita N, Takarn P, Khamnoi P. Highly specific and sensitive detection of Burkholderia pseudomallei genomic DNA by CRISPR-Cas12a. PLoS Negl Trop Dis. 2022 Aug
Chewapreecha C, Pensar J, Chattagul S, Pesonen M, Sangphukieo A, Boonklang P, Potisap C, Koosakulnirand S, Feil EJ, Dunachie S, Chantratita N, Limmathurotsakul D, Peacock SJ, Day NPJ, Parkhill J, Thomson NR, Sermswan RW, Corander J. Co-evolutionary Signals Identify Burkholderia pseudomallei Survival Strategies in a Hostile Environment. Mol Biol Evol. 2022 Jan 7;39(1):msab306. doi: 10.1093/molbev/msab306.
Chewapreecha C, Pensar J, Chattagul S, Pesonen M, Sangphukieo A, Boonklang P, Potisap C, Koosakulnirand S, Feil EJ, Dunachie S, Chantratita N, Limmathurotsakul D, Peacock SJ, Day NPJ, Parkhill J, Thomson NR, Sermswan RW, Corander J. Coevolutionary signals from Burkholderia pseudomallei population genomics highlight its survival strategy in a hostile environment. Molecular Biology and Evolution 2021 https://doi.org/10.1093/molbev/msab306
Fen SHY, Tandhavanant S, Phunpang R, Ekchariyawat P, Saiprom N, Chewapreecha C, Seng R, Thiansukhon E, Morakot C, Sangsa N, Chayangsu S, Chuananont S, Tanwisaid K, Silakun W, Buasi N, Chaisuksant S, Hompleum T, Chetchotisakd P, Day NPJ, Chantratita W, Lertmemongkolchai G, West TE, Chantratita N Antibiotic susceptibility of clinical Burkholderia pseudomallei isolates in northeast Thailand during 2015-2018 and the genomic characterisation of Beta-lactam resistant isoaltes. Antimicrobial Agents and Chemotherapy. 2021. doi: 10.1128/AAC.02230-20
Chomkatekaew C, Boonklang P, Sangphukieo A, Chewapreecha C. An Evolutionary Arms Race between Burkholderia pseudomallei and Host Immune System: What do we know? Frontiers in Microbiology 2021 doi: 10.3389/fmicb.2020.612568
Lehtinen S, Chewapreecha C, Lees J, Hanage WP, Lipsitch M, Croucher NJ, Bentley SD, Turner P, Fraser C, Mostowy RJ. Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae. Science Advances. 2020 May 20; 6(21): eaaz6137. Doi:10.1126/sciadv.aaz6137
Wheeler NE, Reuter S, Chewapreecha C, Lees JA, Blane B, Horner C, Enoch D, Brown N, Torok ME, Aanensen DM, Parkhill J, Peacock SJ. Contrasting approaches to genome-wide association studies impact the detection of resistance mechanisms in Staphylococcus aureus. BioRxiv 2020 doi: https://doi.org/10.1101/758144
Chewapreecha C, Mather AE, Harris SR, Hunt M, Holden MTG, Chaichana C, Wuthikanun V, Dougan G, Day NPJ, Limmathurotsakul D, Parkhill J, Peacock SJ. Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei. Communications Biology. 2019 2, 428 doi:10.1038/s42003-019-0678-x
Pensar J, Puranen S, Arnold B, MacAlasdair N, Kuronen J, Tonkin-Hill G, Pesonen M, Xu Y, Sipola A, Sánchez-Busó L, Lees JA, Chewapreecha C, Bentley SD, Harris SR, Parkhill J, Croucher NJ, Corander J Genome-wide epistasis and co-selection study using mutual information. Nucleic Acids Res. 2019 Oct 10;47(18):e112. Doi:10.1093/nar/gkz656.
Thailand Melioidosis Network (53 authors). Melioidosis in Thailand: present and future. Tropical Medicine and Infectious Disease 2018;3(2):38 . doi:10.3390/tropicalmed3020038
Chewapreecha C, Holden MTG, Vehkala M, Välimäki N, Yang Z, Harris SR, Mather AE, Tuanyok A, De Smet B, Le Hello S, Bizet B, Mayo M, Keim P, Dougan G, Dance DAB, Bart Currie, Parkhill J, Peacock SJ. Global and regional dissemination and evolution of Burkholderia pseudomallei. Nature Microbiology. 2017 Jan23;2:16263. doi:10.1038/nmicrobiol.2016.263
Skwark MJ*, Croucher NJ*, Puranen S, Chewapreecha C, Pesonen M, Xu YY, Turner P, Harris SR, Parkhill J, Bentley SD, Aurell E, Corander J. Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis. PLOS Genetics. 2017 Feb 16;13(2):e1006508. doi: 10.1371/journal.pgen.1006508.
Mostowy R, Croucher NJ, De Maio N, Chewapreecha C, Salter SJ, Turner P, Aanensen DM, Bentley SD, Didelot X, Fraser C. Pneumococcal capsule synthesis locus cps as evolutionary hotspot with potential to generate novel serotypes by recombination. Molecular Biology and Evolution 2017; Jun 8. doi: 10.1093/molbev/msx173.
Lees JA*, Vehkala M*, Välimäki N, Harris SR, Chewapreecha C, Croucher NJ, Marttinen P, Davies MR, Steer AC, Tong SYC, Honkela A, Parkhill J, Bentley SD, Corander J. Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypes. Nature Communications. 2016; 7:12797. Doi: 10.1038/ncomms12797
Chewapreecha C, Benard A, Reuter S. Pathogen hide-and-seq. Nature Review Microbiology 2016; 14(5):271. doi 10.1038/nmicro.2016.52
Numinen E, Chewapreecha C, Turner C, Goldblatt D, Nosten F, Bentley SD, Turner P, Corander J. Climate induces seasonality in pneumococcal transmission. Scientific Reports. 2015; 5:11344. doi: 10.1038/srep11344
Chewapreecha C, Harris SR, Croucher NJ, Turner C, Corander J, Marttinen P, Cheng L, Persia A, Mather AE, Page A, Salter S, Harris D, Goldblatt D, Parkhill J, Turner P*, Bentley SD* Dense genomic sampling identifies highways of pneumococcal recombination. Nature Genetics. 2014;46(3):305- 9. doi: 10.1038/ng.2895
Chewapreecha C, Marttinen P, Croucher NJ, Salter SJ, Harris SR, Mather AE, Hanage WP, Goldblatt D, Nosten FH, Turner C, Turner P*, Bentley SD*, Parkhill J.* Comprehensive identification of single nucleotide polymorphism associated with B-lactam Resistance within pneumococcal mosaic genes. PLOS Genetics. 2014;10(8):e1004547. doi: 10.1371/journal.pgen.1004547
Chewapreecha C. Your gut microbiota are what you eat. Nature Review Microbiology. 2014;12(1):8 doi: 10.1038/nrmicro3186
Numinen E, Chewapreecha C, Siren J, Turner C, Turner P, Bentley SD, Corander J. Two-phase importance sampling for inference about transmission trees. Proc Biol Sci. 2014; 281(1794):20141324. doi: 10.1098/rspb.2014.1324
Croucher NJ, Chewapreecha C, Hanage WP, Harris SR, McGee L, van der Linden M, Song J, Ko KS, de Lencastre H, Turner C, Yang F, Sa-Leao R, Klugman KP, Parkhill J, Turner P, Bentley SD. Evidence for soft selective sweeps in the evolution of pneumococcal multidrug-resistance and vaccine escape. Genome Biology and Evolution. 2014; 6(7):1589-602. doi: 10.1093/gbe/evu120
Hilty M, Wüthrich D, Salter SJ, Engel H, Campbell S, Sá-Leão R, de Lencastre H, Hermans P, Sadowy E, Turner P, Chewapreecha C, Diggle M, Pluschke G, McGee L, Köseoğlu Eser Ö, Low DE, Smith-Vaughan H, Endimiani A, Küffer M, Dupasquier M, Beaudoing E, Weber J, Bruggmann R, Hanage WP, Parkhill J, Hathaway LJ, Mühlemann K, Bentley SD. Global phylogenomic analysis of nonencapsulated Streptococcus pneumonia reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages. Genome Biology and Evolution. 2014 4;6(12):3281-94. doi: 10.1093/gbe/evu263.
Chewapreecha C. Natural Transformers. Nature Review Microbiology. 2012; 10(9):598. doi: 10.1038/nmicro2865.
Bryant J,* Chewapreecha C*, Bentley SD. Developing insights into the mechanisms of evolution of bacterial pathogens from whole genome sequences. Future Microbiolgy. 2012; 7(11):1283-96. doi: 10.2217/fmb.12.108
Everett DB, Cornick J, Denis B, Chewapreecha C, Croucher NJ, Harris SR, Gordon S, Carrol E, French N, Parkhill J, Heyderman RS, Bentley SD. Genetic characterization of Streptococcus pneumoniae in Malawi Prior to the roll out of the 13-valent pneumococcal conjugate vaccine using a high- throughput genome sequencing approach” PLoS-One. 2012 September; 7(9):e44250. doi: 10.1371/journal.pone.0044250
Köser CU, Holden MTG, Ellington MJ, Cartwright EJP, Brown NM, Ogilvy- Stuart AL, Hsu LY, Chewapreecha C, Croucher NJ, Harris SR, Sanders M, Enright MC, Dougan G, Bentley SD, Parkhill J, Fraser LJ, Betley JR, Schulz- Trieglaff OB, Smith GP, Peacock SJ. Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak. New England Journal of Medicine. 2012;363:2267- 2275. doi: 10.1056/NEJMoa1109910.