Name: Natnaree Saiprom
Position: Scientist
Department: Microbiology and Immunology
Chornchoem P, Tandhavanant S, Saiprom N, Preechanukul A, Thongchompoo N, Sensorn I, Chantratita W, Chantratita N. Metagenomic evaluation, antimicrobial activities, and immune stimulation of probiotics from dietary supplements and dairy products. Sci Rep. 2025 Apr 4;15(1):11537. doi: 10.1038/s41598-025-95664-w. PMID: 40185827; PMCID: PMC11971409.
Nimnuan-Ngam S, Hii SYF, Seng R, Saiprom N, Tandhavanant S, West TE, Chantratita N. Identification of novel amrR deletions as meropenem resistance mechanisms in clinical Burkholderia pseudomallei isolates. Microbiol Spectr. 2025 Mar 26;13(5):e0193624. doi: 10.1128/spectrum.01936-24. Epub ahead of print. PMID: 40135925; PMCID: PMC12054045.
Cagape CMS, Seng R, Saiprom N, Tandhavanant S, Chewapreecha C, Boonyuen U, West TE, Chantratita N. Genetic variation, structural analysis, and virulence implications of BimA and BimC in clinical isolates of Burkholderia pseudomallei in Thailand. Sci Rep. 2024 Oct 23;14(1):24966. doi: 10.1038/s41598-024-74922-3.
Wright SW, Ekchariyawat P, Sengyee S, Phunpang R, Dulsuk A, Saiprom N, Thiansukhon E, Pattanapanyasat K, Korbsrisate S, West TE, Chantratita N. Dysfunctional host cellular immune responses are associated with mortality in melioidosis. Emerg Microbes Infect. 2024
Seng R, Chomkatekaew C, Tandhavanant S, Saiprom N, Phunpang R, Thaipadungpanit J, Batty EM, Day NPJ, Chantratita W, West TE, Thomson NR, Parkhill J, Chewapreecha C, Chantratita N. Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in Northeast Thailand. Nat Commun. 2024 Jul 7;15(1):5699. doi: 10.1038/s41467-024-50067-9. PMID: 38972886; PMCID: PMC11228029
Preechanukul A, Saiprom N, Rochaikun K, Moonmueangsan B, Phunpang R, Ottiwet O, Kongphrai Y, Wapee S, Janon R, Dunachie S, Kronsteiner B, Chantratita N. Metabolic requirements of CD160 expressing memory-like NK cells in Gram-negative bacterial infection. Clin Transl Immunology. 2024 Jul 2;13(7):e1513. doi: 10.1002/cti2.1513. PMID: 38957437; PMCID: PMC11218174.
Vannachone S, Luangraj M, Dance D, Chantratita N, Saiprom N, Seng R, Tandhavanant S, Rattanavong S, Simpson A, Roberts T. Case Report: Soft tissue infection with Burkholderia thailandensis capsular variant: case report from the Lao PDR. Wellcome Open Res. 2024 Nov 28;9:421. doi: 10.12688/wellcomeopenres.22706.1.
Wright SW, Ekchariyawat P, Sengyee S, Phunpang R, Dulsuk A, Saiprom N, Thiansukhon E, Pattanapanyasat K, Korbsrisate S, West TE, Chantratita N. Dysfunctional host cellular immune responses are associated with mortality in melioidosis. Emerg Microbes Infect. 2024 Dec;13(1):2380822. doi: 10.1080/22221751.2024.2380822.
Burtnick MN, Dance DAB, Vongsouvath M, Newton PN, Dittrich S, Sendouangphachanh A, Woods K, Davong V, Kenna DTD, Saiprom N, Sengyee S, Hantrakun V, Wuthiekanun V, Limmathurotsakul D, Chantratita N, Brett PJ. Identification of Burkholderia cepacia strains that express a Burkholderia pseudomallei-like capsular polysaccharide. Microbiol Spectr. 2024 Mar 5;12(3):e0332123. doi: 10.1128/spectrum.03321-23.
Preechanukul A, Saiprom N, Rochaikun K, Moonmueangsan B, Phunpang R, Ottiwet O, Kongphrai Y, Wapee S, Janon R, Dunachie S, Kronsteiner B, Chantratita N. Metabolic requirements of CD160 expressing memory-like NK cells in Gram-negative bacterial infection. Clin Transl Immunology. 2024 Jul 2;13(7):e1513. doi: 10.1002/cti2.1513.
Seng R, Chomkatekaew C, Tandhavanant S, Saiprom N, Phunpang R, Thaipadungpanit J, Batty EM, Day NPJ, Chantratita W, West TE, Thomson NR, Parkhill J, Chewapreecha C, Chantratita N. Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in Northeast Thailand. Nat Commun. 2024 Jul 7;15(1):5699. doi: 10.1038/s41467-024-50067-9. P
Preechanukul A, Kronsteiner B, Saiprom N, Rochaikun K, Moonmueangsan B, Phunpang R, Ottiwet O, Kongphrai Y, Wapee S, Chotivanich K, Morakot C, Janon R, Dunachie SJ, Chantratita N. Identification and function of a novel human memory-like NK cell population expressing CD160 in melioidosis. iScience. 2023 Jun 28;26(8):107234. doi: 10.1016/j.isci.2023.107234.
Seng R, Chomkatekaew C, Tandhavanant S, Saiprom N, Phunpang R, Thaipadungpanit J, Batty EM, Day NP, Chantratita W, West TE, Thomson NR, Parkhill J, Chewapreecha C, Chantratita N. Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in northeast Thailand. bioRxiv [Preprint]. 2023 Dec 10:2023.06.02.543359. doi: 10.1101/2023.06.02.543359. Update in: Nat Commun. 2024 Jul 7;15(1):5699. doi: 10.1038/s41467-024-50067-9. PMID: 38106061; PMCID: PMC10723255
Seng R, Phunpang R, Saiprom N, Dulsuk A, Chewapreecha C, Thaipadungpanit J, Batty EM, Chantratita W, West TE, Chantratita N. Phenotypic and genetic alterations of Burkholderia pseudomalleiin patients during relapse and persistent infections. Front Microbiol. 2023 Feb 6;14:1103297. doi: 10.3389/fmicb.2023.1103297.
Saiprom N, Wongsuk T, Oonanant W, Sukphopetch P, Chantratita N, Boonsilp S. Characterization of Virulence Factors in Candida Species Causing Candidemia in a Tertiary Care Hospital in Bangkok, Thailand. J Fungi (Basel). 2023 Mar 14;9(3):353. doi: 10.3390/jof9030353.
Needs SH, Saiprom N, Rafaque Z, Imtiaz W, Chantratita N, Runcharoen C, Thammachote J, Anun S, Peacock SJ, Ray P, Andrews S, Edwards AD. Miniaturised broth microdilution for simplified antibiotic susceptibility testing of Gram negative clinical isolates using microcapillary devices. Analyst. 2022 Jul 22;147(15):3558-3569. doi: 10.1039/d2an00305h.
Fen SH, Tandhavanant S, Phunpang R, Ekchariyawat P, Saiprom N, Chewapreecha C, Seng R, Thiansukhon E, Morakot C, Sangsa N, Chayangsu S. Antibiotic susceptibility of clinical Burkholderia pseudomallei isolates in northeast Thailand during 2015-2018 and the genomic characterization of β-lactam-resistant isolates. Antimicrobial Agents and Chemotherapy. 2021 Feb 16.
Sangsri T, Saiprom N, Tubsuwan A, Monk P, Partridge LJ, Chantratita N. Tetraspanins are involved in Burkholderia pseudomallei-induced cell-to-cell fusion of phagocytic and non-phagocytic cells. Scientific reports. 2020 Oct 21;10(1):1-7.
Saiprom N, Sangsri T, Tandhavanant S, Sengyee S, Phunpang R, Preechanukul A, Surin U, Tuanyok A, Lertmemongkolchai G, Chantratita W, West TE. Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency. PLoS neglected tropical diseases. 2020 Sep 29;14(9):e0008590.
Seng R, Saiprom N, Phunpang R, Baltazar C. J., Boontawee S, Thodthasri T and Chantratita N. Prevalence and genetic diversity of Burkholderia pseudomallei isolates in the environment near a patient’s residence in Northeast Thailand. PLoS One. 2019 Apr ;9;13(4): e0007348. doi: 10.1371/journal.pntd.0007348
Kitti T, Seng R, Saiprom N, Thummeepak R, Chantratita N, Boonlao C and Sitthisak S. Molecular characteristics of methicillin-resistant staphylococci clinical isolates from a tertiary Hospital in Northern Thailand. Can J Infect Dis Med Microbiol. 2018 Nov 19;2018:8457012. doi: 10.1155/2018/8457012. eCollection.
Sengyee S, Saiprom N, Paksanont S, Limmathurotsakul D, Wuthiekanun V and Chantratita N. Susceptibility of Clinical Isolates of Burkholderia pseudomallei to a Lipid A Biosynthesis Inhibitor. Am J Trop Med Hyg. 2017 Jul;97(1):62-67. doi: 10.4269/ajtmh.16-0858.
Withatanung P, Chantratita N, Muangsombut V, Saiprom N, Lertmemongkolchai G, Klumpp J, Clokie MR, Galyov EE and Korbsrisate S. Analyses of the Distribution Patterns of Burkholderia pseudomallei and Associated Phages in Soil Samples in Thailand Suggest That Phage Presence Reduces the Frequency of Bacterial Isolation. PLoS Negl. Trop. Dis. 10: e0005005.doi:10.1371/journal. pntd.0005005
Saiprom N, Amornchai P, Wuthiekanun V, Day NP, Limmathurotsakul D, Peacock SJ, Chantratita N. Trimethoprim/sulfamethoxazole resistance in clinical isolates of Burkholderia pseudomallei from Thailand. International journal of antimicrobial agents. 2015 May;45(5):557.
Wikraiphat C, Saiprom N, Tandhavanant S, Heiss C, Azadi P, Wongsuvan G, Tuanyok A, Holden MT, Burtnick MN, Brett PJ, Peacock SJ and Chantratita N. Colony morphology variation of Burkholderia pseudomallei is associated with antigenic variation and O-polysaccharide modification. Infect Immun. 2015 May; 83(5):2127-38.
Limmathurotsakul D, Paeyao A, Wongratanacheewin S, Saiprom N, Takpho N, Thaipadungpanit J, Chantratita N, Wuthiekanun V, Day NP and Peacock SJ. Role of Burkholderia pseudomallei biofilm formation and lipopolysaccharide in relapse of melioidosis. Clin Microbiol Infect. 2014 Nov;20(11): O854-6
Limmathurotsakul D, Wongsuvan G, Aanensen D, Ngamwilai S, Saiprom N, Rongkard P, Thaipadungpanit J, Kanoksil M, Chantratita N, Day NP, Peacock SJ. Melioidosis caused by Burkholderia pseudomallei in drinking water, Thailand, 2012. Emerging infectious diseases. 2014 Feb;20(2):265.
Thaipadungpanit J, Wuthiekanun V, Chantratita N, Yimsamran S, Amornchai P, Boonsilp S, Maneeboonyang W, Tharnpoophasiam P, Saiprom N, Mahakunkijcharoen Y, Day NP, Singhasivanon P, Peacock SJ and Limmathurotsakul D. Leptospira species in floodwater during the 2011 floods in the Bangkok Metropolitan Region, Thailand. Am J Trop Med Hyg. 2013 Oct;89(4):794-6.
Thanwisai A, Tandhavanant S, Saiprom N, Waterfield NR, Ke Long P, Bode HB, Peacock SJ and Chantratita N. Diversity of Xenorhabdus and Photorhabdus spp. and their symbiotic entomopathogenic nematodes from Thailand. PLoS One. 2012;7(9): e43835
Chantratita N, Tandhavanant S, Wikraiphat C, Trunck LA, Rholl DA, Thanwisai A, Saiprom N, Limmathurotsakul D, Korbsrisate S, Day NP, Schweizer HP and Peacock SJ. Proteomic analysis of colony morphology variants of Burkholderia pseudomallei defines a role for the arginine deiminase system in bacterial survival. J Proteomics. 2012 Jan 4;75(3):1031-42.
Wuthiekanun V, Amornchai P, Saiprom N, Chantratita N, Chierakul W, Koh GC, Chaowagul W, Day NP, Limmathurotsakul D, Peacock SJ. Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand. Antimicrob Agents Chemother. 2011 Nov;55(11):5388-91. doi: 10.1128/AAC.05517-11.
Pumpuang A, Chantratita N, Wikraiphat C, Saiprom N, Day NP, Peacock SJ and Wuthiekanun V. Survival of Burkholderia pseudomallei in distilled water for 16 years. Trans R Soc Trop Med Hyg. 2011 Oct;105 (10):598-600