Name: Asst. Prof.Dr.Wirongrong Chierakul
ชื่อ-สกุล: ผู้ช่วยศาสตราจารย์ ดร.พญ.วิรงค์รอง เจียรกุล
Position: Deputy Dean for Quality Development
Department: Clinical Tropical Medicine
Anunnatsiri S, Chaowagul W, Teparrukkul P, Chetchotisakd P, Tanwisaid K, Khemla S, Narenpitak S, Pattarapongsin M, Kongsawasd W, Pisuttimarn P, Thipmontree W, Mootsikapun P, Chaisuksant S, Chierakul W, Day NPJ, Limmathurotsakul D. A Comparison Between 12 Versus 20 Weeks of Trimethoprim-sulfamethoxazole as Oral Eradication Treatment for Melioidosis: An Open-label, Pragmatic, Multicenter, Non-inferiority, Randomized Controlled Trial. Clin Infect Dis. 2021 Dec 6;73(11):e3627-e33.
Koyama H, Chierakul W, Charunwatthana P, Sanguanwongse N, Phonrat B, Silachamroon U, Dondorp AM. Lung Ultrasound Findings of Patients with Dengue Infection: A Prospective Observational Study. Am J Trop Med Hyg. 2021 Jul 19;105(3):766-770.
Ashton PM, Thanh LT, Trieu PH, Van Anh D, Trinh NM, Beardsley J, Kibengo F, Chierakul W, Dance DAB, Rattanavong S, Davong V, Hung LQ, Chau NVV, Tung NLN, Chan AK, Thwaites GE, Lalloo DG, Anscombe C, Nhat LTH, Perfect J, Dougan G, Baker S, Harris S, Day JN*. Three phylogenetic groups have driven the recent population expansion of Cryptococcus neoformans. Nature Communications. 2019 May; 10: 2035
Beardsley J*, Hoang NLT, Kibengo FM, Tung NLN, Binh TQ, Hung LQ, Chierakul W, Thwaites GE, Chau NVV, Nguyen TTT, Geskus RB, Day JN. Do Intracerebral Cytokine Responses Explain the Harmful Effects of Dexamethasone in Human Immunodeficiency Virus–associated Cryptococcal Meningitis?. Clinical Infectious Diseases. 2019 May; 68(9): 1494–501
Luvira V, Silachamroon U*, Piyaphanee W, Lawpoolsri S, Chierakul W, Leaungwutiwong P, Thawornkuno C, Wattanagoon Y. Etiologies of Acute Undifferentiated Febrile Illness in Bangkok, Thailand. American Journal of Tropical Medicine and Hygiene. 2019 Mar; 100(3): 622-9
Phanichkrivalkosil M, Tanganuchitcharnchai A, Jintaworn S, Kantipong P, Laongnualpanich A, Chierakul W, Paris DH, Richards AL, Wangrangsimakul T, Day NPJ, Blacksell SD*. Determination of Optimal Diagnostic Cut-Offs for the Naval Medical Research Center Scrub Typhus IgM ELISA in Chiang Rai, Thailand. American Journal of Tropical Medicine and Hygiene. 2019 May;100(5): 1134-40
Wright SW, Emond MJ, Lovelace-Macon L, Ducken D, Kashima J, Hantrakun V, Chierakul W, Teparrukkul P, Chantratita N, Limmathurotsakul D, West TE*. Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis. Emerging Microbes & Infections. 2019 Feb; 8(1): 282-90
Hinjoy S, Hantrakun V, Kongyu S, Kaewrakmuk J, Wangrangsimakul T, Jitsuronk S, Saengchun W, Bhengsri S, Akarachotpong T, Thamthitiwat S, Sangwichian O, Anunnatsiri S, Sermswan RW, Lertmemongkolchai G, Tharinjaroen CS, Preechasuth K, Udpaun R, Chuensombut P, Waranyasirikul N, Anudit C, Narenpitak S, Jutrakul Y, Teparrukkul P, Teerawattanasook N, Thanvisej K, Suphan A, Sukbut P, Ploddi K, Sirichotirat P, Chiewchanyon B, Rukseree K, Hongsuwan M, Wongsuwan G, Sunthornsut P, Wuthiekanun V, Sachaphimukh S, Wannapinij P, Chierakul W, Chewapreecha C, Thaipadungpanit J, Chantratita N, Korbsrisate S, Taunyok A, Dunachie S, Palittapongarnpim P, Sirisinha S, Kitphati R, Iamsirithaworn S, Chaowagul W, Chetchotisak P, Whistler T, Wongratanacheewin S, Limmathurotsakul D*. Melioidosis in Thailand: Present and Future. Tropical Medicine and Infectious Disease. 2018 Jun 3(2): 38
Wangrangsimakul T, Althaus T, Mukaka M, Kantipong P, Wuthiekanun V, Chierakul W, Blacksell SD, Day NP, Laongnualpanich A, Paris DH*.Causes of acute undifferentiated fever and the utility of biomarkers in Chiangrai, northern Thailand. PLoS Neglected Tropical Diseases. 2018 May12(5): e0006477
Moek F*, Poe P, Charunwatthana P, Pan-Ngum W, Wattanagoon Y, Chierakul W. The reliability of the clinical examination in predicting hemodynamic status in acute febrile illness in a tropical, resource-limited setting. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2018 Apr 112(4): 200-5
Beardsley J, Wolbers M, Kibengo FM, Ggayi A-BM, Kamali A, Cuc NTK, Binh TQ, Chau NVV, Farrar J, Merson L, Phuong L, Thwaites G, Van Kinh N, Thuy PT, Chierakul W, Siriboon S, Thiansukhon E, Onsanit S, Supphamongkholchaikul W, Chan AK, Heyderman R, Mwinjiwa. Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis. New England Journal of Medicine. 2016 Feb 374(6):542-54
Poovorawan K, Thu AM, Sutherat M, Phumratanaprapin W, Wisedopas N, Luvira V*,Chierakul W. Hepatic lymphoma and Splenic Aspergillosis Mimicking Hepatosplenic Abscesses From Melioidosis in Thailand. Southeast Asian Journal of Tropical Medicine and Public Health. 2016 Mar 47(2):223-6
Wattanakul T, Teerapong P, Plewes K, Newton PN, Chierakul W, Silamut K, Chotivanich K, Ruengweerayut R, White NJ, Dondorp AM, Tarning J*. Pharmacokinetic properties of intramuscular versus oral syrup paracetamol in Plasmodium falciparum malaria. Malaria Journal 2016 Apr 15: 244
Hantrakun V, Chierakul W, Chetchotisakd P, Anunnatsiri S, Currie BJ, Peacock SJ, Day NP, Cheah P, Limmathurotsakul D, Lubell Y.Cost-effectiveness analysis of parenteral antimicrobials for acute melioidosis in Thailand. Trans R Soc Trop Med Hyg. 2015 Jun;109(6):416-8
Lim C, Paris DH, Blacksell SD, Laongnualpanich A, Kantipong P, Chierakul W, Wuthiekanun V, Day NP, Cooper BS, Limmathurotsakul D.How to Determine the Accuracy of an Alternative Diagnostic Test when It Is Actually Better than the Reference Tests: A Re-Evaluation of Diagnostic Tests for Scrub Typhus Using Bayesian LCMs. PLoS One. 2015 May 10(5):e0114930
Day J, Imran D, Ganiem AR, Tjahjani N, Wahyuningsih R, Adawiyah R, Dance D, Mayxay M, Newton P, Phetsouvanh R, Rattanavong S, Chan AK, Heyderman R, van Oosterhout JJ, Chierakul W, Day N, Kamali A, Kibengo F, Ruzagira E, Gray A, Lalloo DG, Beardsley J, Binh TQ, Chau TT, Chau NV, Cuc NT, Farrar J, Hien TT, Van KN, Merson L, Phuong L, Tho LT, Thuy PT, Thwaites G, Wertheim H, and Wolbers M. CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial. Trials 2014;15:441.
West TE, Myers ND, Chantratita N, Chierakul W, Limmathurotsakul D, Wuthiekanun V, Miao EA, Hajjar AM, Peacock SJ, Liggitt HD, and Skerrett SJ. NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis. PLoS Negl Trop Dis 2014 Sep;8(9):e3178.
Chantratita N, Tandhavanant S, Myers ND, Chierakul W, Wuthiekanun V, Mahavanakul W, Limmathurotsakul D, Peacock SJ, and West TE. Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand. PLoS One 2014;9(1):e83285.
Myers ND, Chantratita N, Berrington WR, Chierakul W, Limmathurotsakul D, Wuthiekanun V, Robertson JD, Liggitt HD, Peacock SJ, Skerrett SJ, and West TE. The role of NOD2 in murine and human melioidosis. J Immunol 2014;192(1):300-7.
Chetchotisakd P, Chierakul W, Chaowagul W, Anunnatsiri S, Phimda K, Mootsikapun P, Chaisuksant S, Pilaikul J, Thinkhamrop B, Phiphitaporn S, Susaengrat W, Toondee C, Wongrattanacheewin S, Wuthiekanun V, Chantratita N, Thaipadungpanit J, Day NP, Limmathurotsakul D, and Peacock SJ. Trimethoprim-sulfamethoxazole versus trimethoprim-sulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): a multicentre, double-blind, non-inferiority, randomised controlled trial. Lancet 2014;383(9919):807-14.
Chantratita N, Tandhavanant S, Myers ND, Chierakul W, Robertson JD, Mahavanakul W, Singhasivanon P, Emond MJ, Peacock SJ, and West TE. Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis. Genes Immun 2014;15(2):63-71
Wuthiekanun V, Amornchai P, Paris DH, Langla S, Thaipadunpanit J, Chierakul W, Smythe LD, White NJ, Day NP, Limmathurotsakul D, and Peacock SJ. Rapid isolation and susceptibility testing of Leptospira spp. using a new solid medium, LVW agar. Antimicrob Agents Chemother 2013:57; 297-302.
West TE, Chantratita N, Chierakul W, Limmathurotsakul D, Wuthiekanun V, Myers ND, Emond MJ, Wurfel MM, Hawn TR, Peacock SJ, and Skerrett SJ. Impaired TLR5 functionality is associated with survival in melioidosis. J Immunol 2013:190; 3373-3379.
Sonthayanon P, Chierakul W, Wuthiekanun V, Limmathurotsakul D, Amornchai P, Smythe LD, Day NP, and Peacock SJ. Molecular confirmation of co-infection by pathogenic Leptospira spp. and Orientia tsutsugamushi in patients with acute febrile illness in Thailand. Am J Trop Med Hyg 2013;89(4):797-9.
Saonanon P, Tirakunwichcha S, and Chierakul W. Case report of orbital cellulitis and necrotizing fasciitis from melioidosis. Ophthal Plast Reconstr Surg 2013:29; e81-e84.
Sagaki P, Thanachartwet V, Desakorn V, Sahassananda D, Chamnanchanunt S, Chierakul W, Pitisuttithum P, and Ruangkanchanasetr P. Clinical Factors for Severity of Plasmodium falciparum Malaria in Hospitalized Adults in Thailand. PLoS One 2013:8; e71503.
Newton PN, Stepniewska K, Dondorp A, Silamut K, Chierakul W, Krishna S, Davis TM, Suputtamongkol Y, Angus B, Pukrittayakamee S, Ruangveerayuth R, Hanson J, Day NP, and White NJ. Prognostic indicators in adults hospitalized with falciparum malaria in Western Thailand. Malar J 2013:12; 229.
Kyaw NL, Thanachartwet V, Kiertiburanakul S, Desakorn V, Chamnanchanunt S, Chierakul W, Manosuthi W, Pitisuttithum P, and Sungkanuparph S. Baseline CD4 cell counts and outcomes among adult treatment naive HIV patients after taking fixed dose combination GPO-VIR-S and GPO-VIR-Z in Thailand. Southeast Asian J Trop Med Public Health 2013:44; 232-243.
Bhengsri S, Lertiendumrong J, Baggett HC, Thamthitiwat S, Chierakul W, Tisayaticom K, Tanwisaid K, Chantra S, and Kaewkungwal J. Economic burden of bacteremic melioidosis in eastern and northeastern, Thailand. Am J Trop Med Hyg 2013:89; 369-373.
Aung KL, Thanachartwet V, Desakorn V, Chamnanchanunt S, Sahassananda D, Chierakul W, and Pitisuttithum P. Factors associated with severe clinical manifestation of dengue among adults in Thailand. Southeast Asian J Trop Med Public Health 2013:44; 602-612.
West TE, Chierakul W, Chantratita N, Limmathurotsakul D, Wuthiekanun V, Emond MJ, Hawn TR, Peacock SJ, and Skerrett SJ. Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis. Genes Immun 2012:13; 38-46.
Mahavanakul W, Nickerson EK, Srisomang P, Teparrukkul P, Lorvinitnun P, Wongyingsinn M, Chierakul W, Hongsuwan M, West TE, Day NP, Limmathurotsakul D, and Peacock SJ. Feasibility of modified surviving sepsis campaign guidelines in a resource-restricted setting based on a cohort study of severe S. aureus sepsis [corrected]. PLoS One 2012:7; e29858.
Limmathurotsakul D, Turner EL, Wuthiekanun V, Thaipadungpanit J, Suputtamongkol Y, Chierakul W, Smythe LD, Day NP, Cooper B, and Peacock SJ. Fool's gold: Why imperfect reference tests are undermining the evaluation of novel diagnostics: a reevaluation of 5 diagnostic tests for leptospirosis. Clin Infect Dis 2012:55; 322-331.
Desakorn V, Wuthiekanun V, Thanachartwet V, Sahassananda D, Chierakul W, Apiwattanaporn A, Day NP, Limmathurotsakul D, and Peacock SJ. Accuracy of a commercial IgM ELISA for the diagnosis of human leptospirosis in Thailand. Am J Trop Med Hyg 2012:86; 524-527.
Blacksell SD, Paris DH, Chierakul W, Wuthiekanun V, Teeratakul A, Kantipong P, and Day NP. Prospective evaluation of commercial antibody-based rapid tests in combination with a loop-mediated isothermal amplification PCR assay for detection of Orientia tsutsugamushi during the acute phase of scrub typhus infection. Clin Vaccine Immunol 2012:19; 391-395.
Wuthiekanun V, Amornchai P, Saiprom N, Chantratita N, Chierakul W, Koh GC, Chaowagul W, Day NP, Limmathurotsakul D, and Peacock SJ. Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand. Antimicrob Agents Chemother 2011:55; 5388-5391.
Thaipadungpanit J, Chierakul W, Wuthiekanun V, Limmathurotsakul D, Amornchai P, Boonslip S, Smythe LD, Limpaiboon R, Hoffmaster AR, Day NP, and Peacock SJ. Diagnostic accuracy of real-time PCR assays targeting 16S rRNA and lipL32 genes for human leptospirosis in Thailand: a case-control study. PLoS One 2011:6; e16236.
Sonthayanon P, Chierakul W, Wuthiekanun V, Thaipadungpanit J, Kalambaheti T, Boonsilp S, Amornchai P, Smythe LD, Limmathurotsakul D, Day NP, and Peacock SJ. Accuracy of loop-mediated isothermal amplification for diagnosis of human leptospirosis in Thailand. Am J Trop Med Hyg 2011:84; 614-620.
Paris DH, Blacksell SD, Nawtaisong P, Jenjaroen K, Teeraratkul A, Chierakul W, Wuthiekanun V, Kantipong P, and Day NP. Diagnostic accuracy of a loop-mediated isothermal PCR assay for detection of Orientia tsutsugamushi during acute Scrub Typhus infection. PLoS Negl Trop Dis 2011:5; e1307.
Koh GC, Maude RR, Schreiber MF, Limmathurotsakul D, Wiersinga WJ, Wuthiekanun V, Lee SJ, Mahavanakul W, Chaowagul W, Chierakul W, White NJ, van der Poll T, Day NP, Dougan G, and Peacock SJ. Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis. Clin Infect Dis 2011:52; 717-725.
Boonsilp S, Thaipadungpanit J, Amornchai P, Wuthiekanun V, Chierakul W, Limmathurotsakul D, Day NP, and Peacock SJ. Molecular detection and speciation of pathogenic Leptospira spp. in blood from patients with culture-negative leptospirosis. BMC Infect Dis 2011:11; 338.
Suputtamongkol Y, Pongtavornpinyo W, Lubell Y, Suttinont C, Hoontrakul S, Phimda K, Losuwanaluk K, Suwancharoen D, Silpasakorn S, Chierakul W, and Day N. Strategies for diagnosis and treatment of suspected leptospirosis: a cost-benefit analysis. PLoS Negl Trop Dis 2010; 4(2):e610.
Sonthayanon P, Peacock SJ, Chierakul W, Wuthiekanun V, Blacksell SD, Holden MT, Bentley SD, Feil EJ, and Day NP. High rates of homologous recombination in the mite endosymbiont and opportunistic human pathogen Orientia tsutsugamushi. PLoS Negl Trop Dis 2010; 4(7):e752.
Niwattayakul K, Kaewtasi S, Chueasuwanchai S, Hoontrakul S, Chareonwat S, Suttinont C, Phimda K, Chierakul W, Silpasakorn S, and Suputtamongkol Y. An open randomized controlled trial of desmopressin and pulse dexamethasone as adjunct therapy in patients with pulmonary involvement associated with severe leptospirosis. Clin Microbiol Infect 2010; 16(8):1207-1212.
Brouwer AE, Teparrukkul P, Rajanuwong A, Chierakul W, Mahavanakul W, Chantratita W, White NJ, and Harrison TS. Cerebrospinal fluid HIV-1 viral load during treatment of cryptococcal meningitis. J Acquir Immune Defic Syndr 2010; 53(5):668-669.
Bicanic T A, Muzoora C, Brouwer A E, Meintjes G, Longley N, Taseera K, Rebe K, Loyse A, Jarvis J, Bekker L.-G, Wood R, Limmathurotsakul D, Chierakul W, Stepniewska K, White N J, Jaffar S, Harrison T S. Independent association between rate of clearance of infection and clinical outcome of hiv-associated cryptococcal meningitis: Analysis of a combined cohort of 262 patients. Clin InfecDis 2009; 49 (5):702-709.
Cheng A C, McBryde E S, Wuthiekanun V, Chierakul W, Amornchai P, Day N P J, White N J, Peacock S J. Dosing regimens of cotrimoxazole (trimethoprim-sulfamethoxazole) for melioidosis. Antimicrobial Agents and Chemotherapy 2009;53(10):4193-4199.
Nickerson EK, Hongsuwan M, Limmathurotsakul D, Wuthiekanun V, Shah KR, Srisomang P, Mahavanakul W, Wacharaprechasgul T, Fowler VG, West TE, Teerawatanasuk N, Becher H, White NJ, Chierakul W, Day NP, Peacock SJ. Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance. PLoS ONE. 2009;4(1):e4308. Epub 2009 Jan 30.
Smythe L D, Wuthiekanun V, Chierakul W, Suputtamongkol Y, Tiengrim S, Dohnt M F, Symonds M L, Slack A T, Apiwattanaporn A, Chueasuwanchai S, Day N P, Peacock S J Short report: The microscopic agglutination test (MAT) is an unreliable predictor of infecting Leptospira serovar in Thailand. Am J Trop Med Hyg 2009; 81(4): 695-697.
Sonthayanon P, Chierakul W, Wuthiekanun V, Phimda K, Pukrittayakamee S, Day N.P., Peacock S.J. Association of high Orientia tsutsugamushi DNA loads with disease of greater severity in adults with scrub typhus. Journal of Clinical Microbiology 2009;47 (2), pp. 430-434.
Suputtamongkol Y, Suttinont C, Niwatayakul K, Hoontrakul S, Limpaiboon R, Chierakul W, Losuwanaluk K, Saisongkork W. Epidemiology and clinical aspects of rickettsioses in Thailand Annals of the New York Academy of Sciences 2009;1166:172-179.
Wongsuvan, G., Limmathurotsakul, D., Wannapasni, S., Chierakul, W., Teerawattanasook, N., Wuthiekanun, V. Lack of correlation of burkholderia pseudomallei quantities in blood, urine, sputum and pus. Southeast Asian J Trop Med Public Health 2009;40 (4):781-784.
Cheng AC, Chierakul W, Chaowagul W, Chetchotisakd P, Limmathurotsakul D, Dance DA, Peacock SJ, and Currie BJ. Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis. Am J Trop Med Hyg 2008 Feb;78(2):208-9.
Chierakul W, Tientadakul P, Suputtamongkol Y, Wuthiekanun V, Phimda K, Limpaiboon R, Opartkiattikul N, White NJ, Peacock SJ, and Day NP. Activation of the coagulation cascade in patients with leptospirosis. Clin Infect Dis 2008 Jan;46(2):254-60.
Sonthayanon P, Chierakul W, Wuthiekanun V, Phimda K, Pukrittayakamee S, Day NP, Peacock SJ. High Orientia tsutsugamushi DNA loads are associated with more severe disease in adults with scrub typhus. J Clin Microbiol. 2008 Dec 17.
Tumapa S, Holden MT, Vesaratchavest M, Wuthiekanun V, Limmathurotsakul D, Chierakul W, Feil EJ, Currie BJ, Day NP, Nierman WC, and Peacock SJ. Burkholderia pseudomallei genome plasticity associated with genomic island variation. BMC Genomics 2008;9:190.
Thaipadungpanit J, Wuthiekanun V, Chierakul W, Smythe LD, Petkanchanapong W, Limpaiboon R, Apiwatanaporn A, Slack AT, Suputtamongkol Y, White NJ, Feil EJ, Day NP, Peacock SJ. A Dominant Clone of Leptospira interrogans Associated with an Outbreak of Human Leptospirosis in Thailand. PLoS Negl Trop Dis. 2007 Oct 31;1(1):e56.
Amornchai P, Chierakul W, Wuthiekanun V, Mahakhunkijcharoen Y, Phetsouvanh R, Currie BJ, Newton PN, van Vinh CN, Wongratanacheewin S, Day NP, and Peacock SJ. Accuracy of Burkholderia pseudomallei identification using the API 20NE system and a latex agglutination test. J Clin Microbiol 2007 Nov;45(11):3774-6.
Brouwer AE, van Kan HJ, Johnson E, Rajanuwong A, Teparrukkul P, Wuthiekanun V, Chierakul W, Day N, and Harrison TS. Oral versus intravenous flucytosine in patients with human immunodeficiency virus-associated cryptococcal meningitis. Antimicrob Agents Chemother 2007 Mar;51(3):1038-42.
Brouwer AE, Siddiqui AA, Kester MI, Sigaloff KC, Rajanuwong A, Wannapasni S, Chierakul W, and Harrison TS. Immune dysfunction in HIV-seronegative, Cryptococcus gattii meningitis. J Infect 2007 Mar;54(3):e165-e168.
Chantratita N, Wuthiekanun V, Boonbumrung K, Tiyawisutsri R, Vesaratchavest M, Limmathurotsakul D, Chierakul W, Wongratanacheewin S, Pukritiyakamee S, White NJ, Day NP, and Peacock SJ. Biological relevance of colony morphology and phenotypic switching by Burkholderia pseudomallei. J Bacteriol 2007 Feb;189(3):807-17.
Chantratita N, Wuthiekanun V, Thanwisai A, Limmathurotsakul D, Cheng AC, Chierakul W, Day NP, and Peacock SJ. Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis. Clin Vaccine Immunol 2007 Jan;14(1):110-3.
Cheng AC, Limmathurotsakul D, Chierakul W, Getchalarat N, Wuthiekanun V, Stephens DP, Day NP, White NJ, Chaowagul W, Currie BJ, and Peacock SJ. A randomized controlled trial of granulocyte colony-stimulating factor for the treatment of severe sepsis due to melioidosis in Thailand. Clin Infect Dis 2007 Aug;45(3):308-14.
Chierakul W, Anunnatsiri S, Chaowagul W, Peacock SJ, Chetchotisakd P, and Day NP. Addition of trimethoprim-sulfamethoxazole to ceftazidime during parenteral treatment of melioidosis is not associated with a long-term outcome benefit. Clin Infect Dis 2007 Aug;45(4):521-3.
De Fost M, Chierakul W, Limpaiboon R, Dondorp A, White NJ, and van der PT. Release of granzymes and chemokines in Thai patients with leptospirosis. Clin Microbiol Infect 2007 Apr;13(4):433-6.
Larsen RA, Bauer M, Brouwer AE, Sanchez A, Thomas AM, Rajanuwong A, Chierakul W, Peacock SJ, Day N, White NJ, Rinaldi MG, and Harrison TS. In vitro-clinical correlations for amphotericin B susceptibility in AIDS-associated cryptococcal meningitis. Antimicrob Agents Chemother 2007 Jan;51(1):343-5.
Luksameetanasan R, Blacksell SD, Kalambaheti T, Wuthiekanun V, Chierakul W, Chueasuwanchai S, Apiwattanaporn A, Stenos J, Graves S, Peacock SJ, and Day NP. Patient and sample-related factors that effect the success of in vitro isolation of Orientia tsutsugamushi. Southeast Asian J Trop Med Public Health 2007 Jan;38(1):91-6.
Phimda K, Hoontrakul S, Suttinont C, Chareonwat S, Losuwanaluk K, Chueasuwanchai S, Chierakul W, Suwancharoen D, Silpasakorn S, Saisongkorh W, Peacock SJ, Day NP, and Suputtamongkol Y. Doxycycline versus azithromycin for treatment of leptospirosis and scrub typhus. Antimicrob Agents Chemother 2007 Sep;51(9):3259-63.
Thaipadungpanit J, Wuthiekanun V, Chierakul W, Smythe LD, Petkanchanapong W, Limpaiboon R, Apiwatanaporn A, Slack AT, Suputtamongkol Y, White NJ, Feil EJ, Day NP, and Peacock SJ. A Dominant Clone of Leptospira interrogans associated with an outbreak of human leptospirosis in Thailand. PLoS Negl Trop Dis 2007;1(1):e56.
Wiersinga WJ, Wieland CW, Dessing MC, Chantratita N, Cheng AC, Limmathurotsakul D, Chierakul W, Leendertse M, Florquin S, de Vos AF, White N, Dondorp AM, Day NP, Peacock SJ, and van der PT. Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis). PLoS Med 2007 Jul;4(7):e248.
Wuthiekanun V, Limmathurotsakul D, Wongsuvan G, Chierakul W, Teerawattanasook N, Teparrukkul P, Day NP, and Peacock SJ. Quantitation of B. pseudomallei in clinical samples. Am J Trop Med Hyg 2007 Nov;77(5):812-3.
Wuthiekanun V, Sirisukkarn N, Daengsupa P, Sakaraserane P, Sangkakam A, Chierakul W, Smythe LD, Symonds ML, Dohnt MF, Slack AT, Day NP, and Peacock SJ. Clinical diagnosis and geographic distribution of leptospirosis, Thailand. Emerg Infect Dis 2007 Jan;13(1):124-6.
Wuthiekanun V, Chierakul W, Limmathurotsakul D, Smythe LD, Symonds ML, Dohnt MF, Slack AT, Limpaiboon R, Suputtamongkol Y, White NJ, Day NP, and Peacock SJ. Optimization of culture of Leptospira from humans with leptospirosis. J Clin Microbiol 2007 Apr;45(4):1363-5.
Brouwer AE, Siddiqui AA, Kester MI, Sigaloff KC, Rajanuwong A, Wannapasni S, Chierakul W, and Harrison TS. Immune dysfunction in HIV-seronegative, Cryptococcus gattii meningitis. J Infect, Nov 2006;
Cheng AC, Peacock SJ, Limmathurotsakul D, Wongsuvan G, Chierakul W, Amornchai P, Getchalarat N, Chaowagul W, White NJ, Day NP, and Wuthiekanun V. Prospective evaluation of a rapid immunochromogenic cassette test for the diagnosis of melioidosis in northeast Thailand. Trans R Soc Trop Med Hyg , Jan 2006;100:64-7.
Chierakul W , Wangboonskul J, Singtoroj T, Pongtavornpinyo W, Short JM, Maharjan B, Wuthiekanun V, Dance DA, Teparrukkul P, Lindegardh N, Peacock SJ, Day NP, Chaowagul W, and White NJ. Pharmacokinetic and pharmacodynamic assessment of co-amoxiclav in the treatment of melioidosis. J Ant im icrob Chemother , Sep 2006;58:1215-1220.
Chantratita N, Wuthiekanun V, Thanwisai A, L im mathurotsakul D, Cheng AC, Chierakul W, Day NP, and Peacock SJ. Accuracy of ELISA using crude and purified antigens for the serodiagnosis of melioidosis. Clin Vaccine Immunol, Nov 2006;
Chantratita N, Wuthiekanun V, Boonbumrung K, Tiyawisutsri R, Vesaratchavest M, L im mathurosakul D, Chierakul W, Wongratanacheewin S, Pukritiyakamee S, White NJ, Day NP, and Peacock SJ. Biological relevance of colony morphology and phenotypic switching by Burkholderia pseudomallei. J Bacteriol, Nov 2006;
L im mathurotsakul D, Chaowagul W, Chierakul W, Stepniewska K, Maharjan B, Wuthiekanun V, White NJ, Day NP, and Peacock SJ. Risk factors for recurrent melioidosis in northeast Thailand . Clin Infect Dis , Oct 2006;43:979-986.
Newton PN, Ward S, Angus BJ, Chierakul W, Dondorp A, Ruangveerayuth R, Silamut K, Teerapong P, Suputtamongkol Y, Looareesuwan S, and White NJ. Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations. Trans R Soc Trop Med Hyg , Feb 2006;100;184-186.
Newton PN, Barnes KI, Smith PJ, Evans AC, Chierakul W, Ruangveerayuth R, and White NJ. The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria. Eur J Clin Pharmacol, Dec 2006;62:1003-1009.
Sonthayanon P, Chierakul W, Wuthiekanun V, Blacksell SD, P im da K, Suputtamongkol Y, Pukrittayakamee S, White NJ, Day NP, and Peacock SJ. Rapid diagnosis of scrub typhus in rural Thailand using polymerase chain reaction. Am J Trop Med Hyg , Dec 2006;75:1099-1102.
Wuthiekanun V, Chierakul W, Rattanalertnavee J, Langla S, Sirodom D, Wattanawaitunechai C, Winothai W, White NJ, Day N, and Peacock SJ. Serological evidence for increased human exposure to Burkholderia pseudomallei following the tsunami in Southern Thailand . J Clin Microbiol, Jan 2006;44:239-240.
Wuthiekanun V, Chierakul W, Langa S, Chaowagul W, Pan pitpat C, Saipan P, Thoujaikong T, Day NP, and Peacock SJ. Development of antibodies to Burkholderia pseudomallei during childhood in melioidosis-endemic northeast Thailand . Am J Trop Med Hyg, Jun 2006;74:1074-1075.
Vesaratchavest M, Tumapa S, Day NP, Wuthiekanun V, Chierakul W, Holden MT, White NJ, Currie BJ, Spratt BG, Feil EJ, and Peacock SJ. Nonrandom distribution of Burkholderia pseudomallei clones in relation to geographical location and virulence. J Clin Microbiol, Jul 2006;44:2553-2557.
Wuthiekanun V, Langa S, Swaddiwudhipong W, Jedsadapanpong W, Kaengnet Y, Chierakul W, Day NP, and Peacock SJ. Short report: Melioidosis in Myanmar : forgotten but not gone? Am J Trop Med Hyg, Nov 2006;75:945-946.
Brouwer AE, Teparrukkul P, Pinpraphaporn S, Larsen RA, Chierakul W, Peacock S, Day N, White NJ, and Harrison TS. Baseline correlation and comparative kinetics of cerebrospinal fluid colony-forming unit counts and antigen titers in cryptococcal meningitis. J Infect Dis , Aug 2005;192:681-684.
Cheng AC, Peacock SJ, Limmathurotsakul D, Wongsuvan G, Chierakul W, Amornchai P, Getchalarat N, Chaowagul W, White NJ, Day NP, and Wuthiekanun V. Prospective evaluation of a rapid immunochromogenic cassette test for the diagnosis of melioidosis in northeast Thailand. Trans R Soc Trop Med Hyg , Sep 2005
Chierakul W, Winothai W, Wattanawaitunechai C, Wuthiekanun V, Rugtaengan T, Rattanalertnavee J, Jitpratoom P, Chaowagul W, Singhasivanon P, White NJ, Day NP, and Peacock SJ. Melioidosis in 6 tsunami survivors in southern Thailand. Clin Infect Dis , Oct 2005;41:982-990.
Chierakul W, Anunnatsiri S, Short JM, Maharjan B, Mootsikapun P, Simpson AJ, Limmathurotsakul D, Cheng AC, Stepniewska K, Newton PN, Chaowagul W, White NJ, Peacock SJ, Day NP, and Chetchotisakd P. Two randomized controlled trials of ceftazidime alone versus ceftazidime in combination with trimethoprim-sulfamethoxazole for the treatment of severe melioidosis. Clin Infect Dis , Oct 2005;41:1105-1113.
Chaowagul W, Chierakul W, Simpson AJ, Short JM, Stepniewska K, Maharjan B, Rajchanuvong A, Busarawong D, Limmathurotsakul D, Cheng AC, Wuthiekanun V, Newton PN, White NJ, Day NP, and Peacock SJ. Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidosis. Antimicrob Agents Chemother , Oct 2005;49:4020-4025.
Chierakul W, Wuthiekanun V, Chaowagul W, Amornchai P, Cheng AC, White NJ, Day PJ, and Peacock SJ. Short report: Disease severity and outcome of melioidosis in HIV coinfected individuals. Am J Trop Med Hyg, Dec 2005;73:1165-1166
De Fost M, Chierakul W, Pimda K, Dondorp AM, White NJ, and Van Der PT. Activation of cytotoxic lymphocytes in patients with scrub typhus. Am J Trop Med Hyg , Apr 2005;72:465-467.
Limmathurotsakul D, Wuthiekanun V, Chierakul W, Cheng AC, Maharjan B, Chaowagul W, White NJ, Day NP, and Peacock SJ. Role and significance of quantitative urine cultures in diagnosis of melioidosis. J Clin Microbiol , May 2005;43:2274-2276.
Maharjan B, Chantratita N, Vesaratchavest M, Cheng A, Wuthiekanun V, Chierakul W, Chaowagul W, Day NP, and Peacock SJ. Recurrent melioidosis in patients in northeast Thailand is frequently due to reinfection rather than relapse. J Clin Microbiol , Dec 2005;43:6032-6034.
Newton PN, Chaulet JF, Brockman A, Chierakul W, Dondorp A, Ruangveerayuth R, Looareesuwan S, Mounier C, and White NJ. Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria. Antimicrob Agents Chemother , Apr 2005;49:1622-1625.
Peacock SJ, Chieng G, Cheng AC, Dance DA, Amornchai P, Wongsuvan G, Teerawattanasook N, Chierakul W, Day NP, and Wuthiekanun V. Comparison of Ashdown's medium, Burkholderia cepacia medium, and Burkholderia pseudomallei selective agar for clinical isolation of Burkholderia pseudomallei . J Clin Microbiol , Oct 2005;43:5359-5361.
Siddiqui AA, Brouwer AE, Wuthiekanun V, Jaffar S, Shattock R, Irving D, Sheldon J, Chierakul W, Peacock S, Day N, White NJ, and Harrison TS. IFN-{gamma} at the site of infection determines rate of clearance of infection in cryptococcal meningitis. J Immunol, Feb 2005;174:1746-1750.
Tiyawisutsri R, Peacock SJ, Langa S, Limmathurotsakul D, Cheng AC, Chierakul W, Chaowagul W, Day NP, and Wuthiekanun V. Antibodies from patients with melioidosis recognize Burkholderia mallei but not Burkholderia thailandensis antigens in the indirect hemagglutination assay. J Clin Microbiol , Sep 2005;43:4872-4874.
Veld DH, Wuthiekanun V, Cheng AC, Chierakul W, Chaowagul W, Brouwer AE, White NJ, Day NP, and Peacock SJ. The role and significance of sputum cultures in the diagnosis of melioidosis. Am J Trop Med Hyg , Oct 2005;73:657-661.
Wuthiekanun V, Mayxay M, Chierakul W, Phetsouvanh R, Cheng AC, White NJ, Day NP, and Peacock SJ. Detection of Burkholderia pseudomallei in soil within the Lao People's Democratic Republic. J Clin Microbiol , Feb 2005;43:923-924.
Wuthiekanun V, Desakorn V, Wongsuvan G, Amornchai P, Cheng AC, Maharjan B, Limmathurotsakul D, Chierakul W, White NJ, Day NP, and Peacock SJ. Rapid immunofluorescence microscopy for diagnosis of melioidosis. Clin Diagn Lab Immunol , Apr 2005;12:555-556.
Wuthiekanun V, Cheng AC, Chierakul W, Amornchai P, Limmathurotsakul D, Chaowagul W, Simpson AJ, Short JM, Wongsuvan G, Maharjan B, White NJ, and Peacock SJ. Trimethoprim/sulfamethoxazole resistance in clinical isolates of Burkholderia pseudomallei . J Antimicrob Chemother , Jun 2005;55:1029-1031.
Brouwer AE, Rajanuwong A, Chierakul W, Griffin GE, Larsen RA, White NJ, and Harrison TS. Combination antifungal therapies for HIV-associated cryptococcal meningitis: a randomised trial. Lancet , May 2004;363:1764-1767.
Chierakul W, Rajanuwong A, Wuthiekanun V, Teerawattanasook N, Gasiprong M, Simpson A, Chaowagul W, and White NJ. The changing pattern of bloodstream infections associated with the rise in HIV prevalence in northeastern Thailand. Trans R Soc Trop Med Hyg , Nov 2004;98:678-686.
Chierakul W, De Fost M, Suputtamongkol Y, Limpaiboon R, Dondorp A, White NJ, and Van Der PT. Differential expression of interferon-gamma and interferon-gamma-inducing cytokines in Thai patients with scrub typhus or leptospirosis. Clin Immunol , Nov 2004;113:140-144.
Chotivanich K, Udomsangpetch R, Chierakul W, Newton PN, Ruangveerayuth R, Pukrittayakamee S, Looareesuwan S, and White NJ. In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand. Am J Trop Med Hyg , Apr 2004;70:395-397.
Suputtamongkol Y, Niwattayakul K, Suttinont C, Losuwanaluk K, Limpaiboon R, Chierakul W, Wuthiekanun V, Triengrim S, Chenchittikul M, and White NJ. An open, randomized, controlled trial of penicillin, doxycycline, and cefotaxime for atients with severe leptospirosis. Clin Infect Dis , Nov 2004;39:1417-1424.
Wuthiekanun V, Amornchai P, Chierakul W, Cheng AC, White NJ, Peacock SJ, and Day NP. Evaluation of immunoglobulin M (IgM) and IgG rapid cassette test kits for diagnosis of melioidosis in an area of endemicity. J Clin Microbiol , Aug 2004;42:3435-3437.
Newton PN, Angus BJ, Chierakul W, Dondorp A, Ruangveerayuth R, Silamut K, Teerapong P, Suputtamongkol Y, Looareesuwan S, and White NJ. Randomized comparison of artesunate and quinine in the treatment of severe falciparum malaria. Clin Infect Dis , Jul 2003;37:7-16.
Newton PN, Chierakul W, Ruangveerayuth R, Abhigantaphand D, Looareesuwan S, and White NJ. Malaria and amphetamine 'horse tablets' in Thailand. Trop Med Int Health , Jan 2003;8:17-18.
Simpson AJ, Newton PN, Chierakul W, Chaowagul W, and White NJ. Diabetes mellitus, insulin, and melioidosis in Thailand. Clin Infect Dis , Mar 2003;36:e71-e72.
Suputtamongkol Y, Rolain JM, Losuwanaruk K, Niwatayakul K, Suttinont C, Chierakul W, Pimda K, and Raoult D. Q fever in Thailand. Emerg Infect Dis , Sep 2003;9:1186-1187.
Chotivanich K, Udomsangpetch R, Pattanapanyasat K, Chierakul W, Simpson J, Looareesuwan S, and White N. Hemoglobin E: a balanced polymorphism protective against high parasitemias and thus severe P falciparum malaria. Blood , Aug 2002;100:1172-1176.
Newton PN, Thai lH, Tip NQ, Short JM, Chierakul W, Rajanuwong A, Pitisuttithum P, Chasombat S, Phonrat B, Maek AN, Teaunadi R, Lalloo DG, and White NJ. A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis. Clin Infect Dis , Sep 2002;35:769-772.
Newton PN, Chotivanich K, Chierakul W, Ruangveerayuth R, Teerapong P, Silamut K, Looareesuwan S, and White NJ. A comparison of the in vivo kinetics of Plasmodium falciparum ring-infected erythrocyte surface antigen-positive and -negative erythrocytes. Blood , Jul 2001;98:450-457.
Newton PN, Chierakul W, Ruangveerayuth R, Silamut K, Teerapong P, Krudsood S, Looareesuwan S, and White NJ. A comparison of artesunate alone with combined artesunate and quinine in the parenteral treatment of acute falciparum malaria. Trans R Soc Trop Med Hyg , Sep 2001;95:519-523.
Chierakul, W. (2014). Leptospirosis. In Manson's Tropical Diseases (23rd ed., pp. 433-440). Oxford, UK: Elsevier.
Cheirakul, W. & Chetchotsakdi, P. (2012). Parenteral antimicrobial therapy for melioidosis. In Melioidosis - A century of observation and research (pp. 185-196). Amsterdam, The Netherlands: Elsevier.