Wang Nguitragool

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Molecular Biology team leader | Drug & Vaccine Development

Ph.D. Biophysics , Brandeis University, USA
My current research aims to understand of malaria parasite biology and mosquito infectivity, with an emphasis to develop novel vaccines for malaria. I also lead a molecular diagnosis team for malaria epidemiological studies.

Email: wang.ngu@mahidol.edu

Publications | ResearchGate | Mahidol Profile | LinkedIn

Crary JI, Dean DM, Nguitragool W, Kurshan PT, Zimmerman AL. Mechanism of inhibition of cyclic nucleotide-gated ion channels by diacylglycerol. J Gen Physiol. 2000 Dec;116(6):755-68. doi: 10.1085/jgp.116.6.755. PubMed PMID: 11099345; PubMed Central PMCID: PMC2231817.

Dean DM, Nguitragool W, Miri A, McCabe SL, Zimmerman AL. All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: a novel role for photoreceptor retinoids in the response to bright light?. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8372-7. doi: 10.1073/pnas.122681899. Epub 2002 May 28. PubMed PMID: 12034887; PubMed Central PMCID: PMC123074.

McCabe SL, Pelosi DM, Tetreault M, Miri A, Nguitragool W, Kovithvathanaphong P, Mahajan R, Zimmerman AL. All-trans-retinal is a closed-state inhibitor of rod cyclic nucleotide-gated ion channels. J Gen Physiol. 2004 May;123(5):521-31. doi: 10.1085/jgp.200409011. Epub 2004 Apr 12. PubMed PMID: 15078915; PubMed Central PMCID: PMC2234497.

Accardi A, Walden M, Nguitragool W, Jayaram H, Williams C, Miller C. Separate ion pathways in a Cl-/H+ exchanger. J Gen Physiol. 2005 Dec;126(6):563-70. doi: 10.1085/jgp.200509417. PubMed PMID: 16316975; PubMed Central PMCID: PMC2266597.

Nguitragool W, Miller C. Uncoupling of a CLC Cl-/H+ exchange transporter by polyatomic anions. J Mol Biol. 2006 Sep 29;362(4):682-90. doi: 10.1016/j.jmb.2006.07.006. Epub 2006 Aug 14. PubMed PMID: 16905147.

Nguitragool W, Miller C. CLC Cl /H+ transporters constrained by covalent cross-linking. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20659-65. doi: 10.1073/pnas.0708639104. Epub 2007 Dec 18. PubMed PMID: 18093952; PubMed Central PMCID: PMC2409211.

Miller C, Nguitragool W. A provisional transport mechanism for a chloride channel-type Cl-/H+ exchanger. Philos Trans R Soc Lond B Biol Sci. 2009 Jan 27;364(1514):175-80. doi: 10.1098/rstb.2008.0138. PubMed PMID: 18977737; PubMed Central PMCID: PMC2674093.

Nguitragool W, Bokhari AA, Pillai AD, Rayavara K, Sharma P, Turpin B, Aravind L, Desai SA. Malaria parasite clag3 genes determine channel-mediated nutrient uptake by infected red blood cells. Cell. 2011 May 27;145(5):665-77. doi: 10.1016/j.cell.2011.05.002. PubMed PMID: 21620134; PubMed Central PMCID: PMC3105333.

Alkhalil A, Hong L, Nguitragool W, Desai SA. Voltage-dependent inactivation of the plasmodial surface anion channel via a cleavable cytoplasmic component. Biochim Biophys Acta. 2012 Mar;1818(3):367-74. doi: 10.1016/j.bbamem.2011.11.010. Epub 2011 Nov 13. PubMed PMID: 22115742; PubMed Central PMCID: PMC3273553.