Japanese encephalitis and vaccines
Japanese encephalitis (JE) is an inflammatory disease in the central nervous system including cerebrum, cerebellum, and spinal cord caused by viral infection transmitted by Culex mosquitoes. JE is an important disease in East, Southeast, and South Asia, which lead to serious complication and high mortality rate. Complete cure is shown in only one third of the patients. However the ratio of symptomatic infection with neurological manifestation and asymptomatic infection is 1:25 to 1000. There is no any effective treatment however prevention of JE is possible by avoiding visits to epidemic season, avoiding mosquito bites, and receiving vaccine.