Name: Pornsawan (Amarapal) Leaungwutiwong
Position: Associate Professor
Department: Microbiology and Immunology
Imad H, Phadungsombat J, Nakayama E, Kludkleeb S, MatseeW, Ponam T, Suzuki K, Leaungwutiwong P, Piyaphanee W, Phumratanaprapin W, Shioda T. Chikungunya Manifestations and Viremia in Patients Who Presented to the Fever Clinic at Bangkok Hospital for Tropical Diseases during the 2019 Outbreak in Thailand. Trop Med Infect Dis.2021 Jan 21;6(1):12. doi: 10.3390/tropicalmed6010012.
Imad HA, Matsee W, Kludkleeb S, Asawapaithulsert P, Phadungsombat J, Nakayama EE, Suzuki K, Leaungwutiwong P, et al. Post–Chikungunya Virus Infection Musculoskeletal Disorders: Syndromic Sequelae after an Outbreak. Preprints. 2021. 2021030680 (doi:10.20944/preprints202103.0680.v1).
Imed H, Phadungsombat J, Nakayama E, Suzuki K, Ibrahim A, Afaa A, Azeema A, Nazfa A, Yazfa A, Ahmed A, Saeed A, Waheed A, Shareefa F, Islam M, Anees S, Saleem S, Aroosha A, Afzal I, Leaungwutiwong P, Piyaphanee W, Phumratanaprapin W and Shioda T. Clinical features of acute Chikungunya virus infection in children and adults during an outbreak in the Maldives. Am J Trop Med Hyg. 2021. (In press)
Luvira V, Jittmittraphap A, Muangnoicharoen S, Chantawat N, Janwitthayanan W, Leaungwutiwong P. Temporal Change of SARS-CoV-2 in Clinical Specimens of COVID- 19 pneumonia Patients. Am J Trop Med Hyg. 2020 Jul 8. doi: 10.4269/ajtmh.20-0551.
Nunthavichitra S, Prapaso S, Luvira V, Muangnoicharoen S, Leaungwutiwong P, Piyaphanee W. Case Report: COVID-19 Presenting as Acute Undifferentiated Febrile Illness-A Tropical World Threat. Am J Trop Med Hyg. 2020 May 15. doi: 10.4269/ajtmh.20-0440.
Suzuki K, Huits R, Phadungsombat J, Tuekprakhon A, Nakayama EE, van den Berg R, Barbé B, Cnops L, Rahim R, Hasan A, Iwamoto H, Leaungwutiwong P, van Esbroeck M, Rahman M, Shioda T. Promising application of monoclonal antibody against chikungunya virus E1-antigen across genotypes in immunochromatographic rapid diagnostic tests.Virol J. 2020 Jul 2;17(1):90. doi: 10.1186/s12985-020-01364-4.
John AM, Jittmittraphap A, Chattanadee S, Alwin Prem Anand A, Shenbagarathai R, Leaungwutiwong P. In vitro analysis of synthetic peptides in blocking the entry of dengue virus. Virus Res. 2019; 260: 142-50.
John AM, Jittmittraphap A, Chattanadee S, Alwin Prem Anand A, Shenbagarathai R, Leaungwutiwong P. In vitro analysis of synthetic peptides in blocking the entry of dengue virus. Virus Res. 2019; 260: 142-50.
Suwanmanee S, Mahakhunkijcharoen Y, Ampawong S, Leaungwutiwong P, Misse D, Luplertlop N. Inhibition of N-myristoyltransferase 1 affects dengue virus replication. MicrobiologyOpen. 2019; DOI: 10.1002/mbo3.831.
Luvira V, Silachamroon U, Piyaphanee W, Lawpoolsri S, Chierakul W, Leaungwutiwong P, Thawornkuno C, Wattanagoon Y. Etiologies of Acute Undifferentiated Febrile Illness in Bangkok, Thailand. 2019; 29(5): 197-204. doi: 10.2188/jea.JE20180007.
Sricharunrat T, Pumirat P, Leaungwutiwong P. Oral tolerance: Recent advances on mechanisms and potential applications. Asian Pac J Allerg Immunol 2018; 36(4): 207-16.
Tuekprakhon A, Puiprom O, Sasaki T, Michiels J, Bartholomeeusen K, Nakayama EE, Meno MK, Phadungsombat J, Huits R, Ariën KK, Luplertlop N, Shioda T, Leaungwutiwong P. Broad-spectrum monoclonal antibodies against chikungunya virus structural proteins: Promising candidates for antibodybased rapid diagnostic test development. PLoS One. 2018 doi:10.1371/journal.pone.0208851.
Kosoltanapiwat N, Reamtong O, Okabayashi T, Ampawong S, Rungruengkitkun A, Thiangtrongjit T, Thippornchai N, Leaungwutiwong P, Mahittikorn A, Mori H, Yoohanngoa T, Yamwong P. Mass spectrometry-based identification and whole-genome characterisation of the first pteropine orthoreovirus isolated from monkey faeces in Thailand. BMC Microbiol. 2018. doi: 10.1186/s12866-018-1302-9.
Income N, Kosoltanapiwat N, Taksinoros S, Leaungwutiwong P, Maneekan P, Chavez IF. Molecular identification of enteroviruses from cattle and goat feces and environment in Thailand. Appl Environ Microbiol. 2018. pii: AEM.02420-18. doi: 10.1128/AEM.02420-18.
Mary JA, Jittmittraphap A, Chattanadee S, Leaungwutiwong P, Shenbagarathai R. A synthetic peptide derived from domain III envelope glycoprotein of Dengue virus induces neutralizing antibody. Virus Genes. 2017. doi: 10.1007/s11262-017-1508-1.
Tuekprakhon A, Nakayama E, Bartholomeeusen K, Puiprom O, Sasaki T, Huits R, Luplertlop N, Kosoltanapiwat N, Maneekan P, Arien K, Shioda T, Leaungwutiwong P. Variation at position 350 in the Chikungunya virus 6K-E1 protein determines the sensitivity of detection in a rapid E1-antigen test. Sci Rep. 2017. doi:10.1038/s41598-018-19174-8.
Kosoltanapiwat N, Yindee M, Chavez IF; Leaungwutiwong P, Adisakwattana P, Singhasivanon P, Thawornkuno C, Thippornchai N, Rungruengkitkun A, Soontorn J, Pearsiriwuttipong S. Genetic Variations in Regions of Bovine and Bovine-like Enteroviral 5'UTR from Cattle, Indian Bison and Goat Feces. Virol J 2016; 13: 1-10.
Leaungwutiwong P, Kelley JF, Sachair A, Jittmittraphap A, Luplertlop N. Relationship between MMP expression and virulence of dengue virus type-2 infected mosquito and mammalian cells. Jpn J Infect Dis 2016; 1: 45-50.
Rattanamahaphoom J, Leaungwutiwong P, Limkittikul K, Kosoltanapiwat N, Srikaitkhachorn A. Activation of Dengue Virus-Specific T Cells Modulates Vascular Endothelial Growth Factor Receptor 2 Expression. Asian Pac J Allerg Immunol. 2016. doi: 10.12932/AP0810.
Wongthida P, Jengarn J, Narkpuk J, Koonyosying P, Srisutthisamphan K, Wanitchang A, Leaungwutiwong P, Teeravechyan S, Jongkaewwattana A. In vitro and in vivo attenuation of vesicular stomatitis virus (VSV) by phosphoprotein deletion. Plos One 2016. 1(6): e0157287. doi:10.1371 /journal.pone.0157287
Leaungwutiwong P, Bamrungsak B, Jittmittraphap A, Maneekan P, Kosoltanapiwat N, Kalambaheti T, Kelley JF. Molecular genotyping of HPV L1 gene in low-risk and high-risk populations in Bangkok. Sex Transm Dis 2015; 42: 208-17.
Akapirat S, Avihingsanon A, Ananworanich J, Schuetz A, Ramasoota P, Luplertlop N, Ono K, lkuta K, Piraporn U, Kameoka M, Leaungwutiwong P. Variables influencing ANTI-HUNAN Immmunodeficiency virus TYPE-1 Neutralizing human monoclonal antibody (NHMAB) Production from Thai human Immmunodeficiency virus TYPE 1-Infected individuals. Southeast Asian Journal of Tropical Medicine and Public Health. 2013; 44: 825-41.
Bumrungsak B, Petmitr S, Jittmittraphap A, Maneekan P, Akapirat S, Leaungwutiwong P. Prevalence of cervical and anal cytological abnormalities in low-and high-risk sexual behavior populations in Bangkok, Thailand. Thai AIDS Journal. 2013;2 :105-13.
Maneekan P, Leaungwutiwong P, Misse D, Luplertlop N. T helper (TH) 1 and TH2 cytokine expression profile in dengue and malaria infection using magnetic bead-based bio-plex assay. Southeast Asian J Trop Med Public Health. 2013 Jan;44(1):31-6.
Ngaosuwankul N, Thippornchai N, Yamashita A, Morales V R, Tunyong W, Mahakunkijareon Y, Ikuta K, Singhasivanon P, Okabayashi T, Leaungwutiwong P. Detection and characterization of enteric viruses in flood water from the 2011 Thai flood. Jpn J Infect Dis. 2013; 66: 398-403.
Pipattanaboon C, Sasaki T, Nishimura M, Setthapramote C, Pitaksajjakul P, Leaungwutiwong P, Limkittikul K, Puiprom O, Sasayama M, Chaichana P, Okabayashi T, Kurosu T, Ono K, Ramasoota P, Ikuta K. Cross-reactivity of human monoclonal antibodies generated with peripheral blood lymphocytes from dengue patients with Japanese encephalitis virus. Targets and Therapy Biol Targets Ther 2013; 7: 175-87.
Sasaki T, Setthapramote C, Kurosu T, Nishimura M, Asai A, Omokoko MD, Pipattanaboon C, Pitaksajjakul P, Limkittikul K, Subchareon A, Chaichana P, Okabayashi T, Hirai I, Leuangwutiwong P, Misaki R, Fujiyama K, Ono KI, Okuno Y, Ramasoota P, Ikuta K. Dengue virus neutralization and antibody-dependent enhancement activities of human monoclonal antibodies derived from dengue patients at acute phase of secondary infection. Antiviral Res. 2013 Jun;98(3):423-31.
Singchai P, Jittmittraphap A, Luplertlop N, Kalambaheti T, Wongchotigul V, Pongsuwanna Y, Leaungwutiwong P. Comparison of A simple restriction fragment length polymorphism assay and neutralization for subtyping of coxsackie B viruses. JITMM Proceedings. 2013; 2: 11-7.
Wichit S, Yongpradoem H, Surasombatpattana P, Leaungwuttiwong P, Kalambaheti T, Jampangern W, Jittmittraphap A. Cloning and application of recombinant dengue virus prM-M protein for serodiagnosis of dengue virus infection. Southeast Asian J Trop Med Public Health. 2013 Mar;44(2):218-25.
Luvira V, Chamnanchanunt S, Bussaratid V, Leaungwutiwong P, Pitisuttithum P. Seroprevalence of latent cytomegalovirus infection among elderly Thais. Southeast Asian J Trop Med Public Health 2012; 43: 1419-25.
Setthapramote C, Sasaki T, Puiprom O, Limkittikul K, Pitaksajjakul P, Pipattanaboon P, Sasayama M, Leaungwutiwong P, Phumratanaprapin W, Chamnachanan S, Kusolsuk T, Jittmittraphap A, Asai A, Arias JF, Hirai I, Kuhara M, Okuno Y, Kurosu T, Ramasoota P, Ikuta K. Human monoclonal antibodies to neutralize all dengue-virus serotypes using lymphocytes from patients at acute phase of the secondary infection. Biochem Biophys Res Commun. 2012; 423:867-72.
Leaungwutiwong P, Ittiprasert W, Saikhun K, Tong-Ngam P, Akapirat S, Chattanadee S, Kitiyanant Y. Impairment of CD4+CD25+ regulatory T cells in C4-deficient mice. Asian Pacific Journal of Allergy and Immunology. 2011 Sep; 29(3): 220-8
Puiprom O, Yamashita A, Sasayama M, Limkittikul K, Boonha K, Jittmitraphap A, Leaungwutiwong P, Kurosu T, Ramasoota P, Ikuta K. Co-existence of major and minor viral populations from two different origins in patients secondarily infected with dengue virus serotype 2 in Bangkok. Biochemical and Biophysical Research Communications. 2011 Sep; 413(1): 136-42.
Maneekan P, Jittmittraphap A, Leaungwutiwong P, Kaewkangwal J, Luplertlop N. Development of single-tube mutiplex RT-PCR for dengue virus typing. Southeast Asian J Trop Med Public Health. 2009; 40(6): 1254-8.
Pham DA, Leuangwutiwong P, Jittmittraphap A, Luplertlop N, Bach HK, Akkarathamrongsin S, Theamboonlers A, Poovorawan Y. High Prevalence of Hepatitis C Virus Genotype 6 in Vietnam. Asian Pacific Journal of Allergy and Immunology. 2009; 27: 153-60.
Amarapal P, Tantivanich S, Balachandra K, Matsuo K, Pitisutithum P, Chongsa-nguan M. 2005 The role of the Tat gene in the pathogenesis of HIV infection. Southeast Asian J Trop Med Public Health .36(2):352-61.
Siripanth C, Punpoowong B, Amarapal P, Thima N. 2004 Development of Isospora belli in Hct-8, Hep-2, human fibroblast, BEK and Vero culture cells. Southeast Asian J Trop Med Public Health. 35(4):796-800.
Siripanth C, Punpoowong B, Amarapal P, Thima N, Eampokalap B, Kaewkungwal J. 2004 Comparison of Cryptosporidium parvum development in various cell lines for screening in vitro drug testing. Southeast Asian J Trop Med Public Health. 35(3):540-6.
Tantivanich S, Laohapand P, Thaweeboon S, Desakorn V, Wuthinuntiwong P, Chalermtaranukul S, Pansri P, Amarapal P, Balachandra K, Chantratita W, Dhepakson P. 2004 Prevalence of cytomegalovirus, human herpesvirus-6, and Epstein-Barr virus in periodontitis patients and healthy subjects in the Thai population. Southeast Asian J Trop Med Public Health. 35(3):635-40.
Amarapal P., Tantivanich S, Pengsa K, et al. 2001. Rapid diagnosis of cytomegalovirus infection in congenital neonates. Southeast Asian J. Trop. med. Public Health 32:154-157.
Amarapal P., Tantivanich S, Balachandra K. 2001. Prevalence of cytomegalovirus in Thai blood donors by monoclonal staining of blood leukocytes. Southeast Asian J. Tropmed. Public Health 32: 148-153.
Tantivanich S, Amarapal P, Suphadtanaphong V, Siripanth C, Sawatmongkonkul W. 2001. Prevalence of congenital cytomegalovirus and toxoplasma antibodies in Thailand. Southeast Asian J. Trop. med. Public Health 32: 466-469.
Tantivanich S, Suphadtanaphong V, Siripanth C, Desakorn V, Suphanit I, Phromin S, Panakitsuwan S and Amarapal P. 1999. Prevalence of CMV antibodies among various age groups of Thai Population. Southeast Asian J. Trop. Med. Public Health. 30 (2) : 265-268.