Dr. Wanlapa Roobsoong is a scientist in Mahidol Vivax Research Unit (MVRU). She has a Ph.D. in Medical Technology from Mahidol University. She leads a team in MVRU that focuses on G6PD deficiency and cell biology studies. Her research focuses on the molecular mechanism of gametocytogenesis and hypnozoite formation of P. vivax with an emphasis to discover new antimalarial drugs and vaccines. She led the invention of a product called Young Blood, a ready-to-use reticulocyte-like cell generated from immortalized erythroid progenitor. Young red blood cells are required for in vitro culture of P. vivax, which is crucial for drug and vaccine development.
Dr. Wanlapa has a broad background in medical technology, malaria biology especially Plasmodium vivax, with specific training on proteome analysis, in vitro culture of malaria parasites, image analysis of parasites by high resolution fluorescence microscopy, membrane feeding, and flow cytometry analysis. Her research includes the development of in vitro culture system for P. vivax, the development of in vitro invasion inhibition assay of P. vivax for vaccine screening, characterization of the gametocytogenesis of P. vivax, and transcriptomes and proteomes of erythrocytic stage of P. vivax including gametocyte.
Ongoing Research Project(s)
|• Liver-on-Chip for study drug metabolism and infectious diseases
||ทุนสนับสนุนนักวิจัยเฉพาะสาขา Specific League Funds (ทุนมหาวิทยาลัย)
|• Humanized Mouse Model as a Platform for Continuous Propagation of P. vivax in a Laboratory Setting: SCRI-12104SUB
||SCRI (Prime Award: US-DoD)