Currently, any research projects which involving the laboratory study that funded by the National Research Council of Thailand (NRCT) are required to register into the ESPReL system. This stands for Enhancement of Safety Practice of Research Laboratory in Thailand, a computer program which possesses the data collection of the enrolled research laboratory. After the account has been created, ESPReL would send the registered ID to such research laboratory. This program is designed to provide the self-assessment questionnaire (ESPReL checklist). Consequently, all the stakeholders working in such lab are recommended to gather around and complete this checklist. Throughout the above-mentioned ESPReL processes, the strategies of continuously creating the safe practice in research lab will be implemented.